Evidence map›Paper›PMID 40742730›Full record

ArticleThe Journal of general virology2025

Evaluation of pandemic potential of the genotype 4 (G4) swine influenza virus using

Jenny C M Chan, Rachel H H Ching, Hermione H M Kock, Teng Long, John M Nicholls, J S Malik Peiris, Kenrie P Y Hui, Michael C W Chan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of general virology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jenny C M ChanSchool of Public Health, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, PR China.
Rachel H H ChingSchool of Public Health, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, PR China.
Hermione H M KockSchool of Public Health, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, PR China.
Teng LongSchool of Public Health, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, PR China.
John M NichollsDepartment of Pathology, School of Clinical Medicine, LKS Faculty of Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong SAR, PR China.
J S Malik PeirisSchool of Public Health, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, PR China.
Kenrie P Y HuiSchool of Public Health, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, PR China.
Michael C W ChanSchool of Public Health, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, PR China.

Funding

NIAID Centers of Excellence for Influenza Research and Response: Universal Influenza Vaccine Research Activities75N93021C00016 · NIAID · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI WEBBY, RICHARD · 2021 to 2025
$91.4M
NIAID NIH HHS 75N93021C00016
6 · The paper itself

Abstract

Recent studies have reported a genotype 4 (G4) reassortant Eurasian avian-like (EA) H1N1 virus in swine, demonstrating a potential pandemic threat in humans. Here, we have compared the tropism, replication competence and pro-inflammatory cytokine and chemokine induction of the two G4 EA H1N1 strains in parallel with 2009 pandemic H1N1 (H1N1/pdm/09) and A/Quail/HK/G1/1997 H9N2 (G1) using

Indexed as

Influenza A Virus, H1N1 SubtypeInfluenza A Virus, H9N2 SubtypeInfluenza, HumanOrthomyxoviridae InfectionsRespiratory SystemAnimalsCells, CulturedCytokinesGenotypeHumansMacrophagesPandemicsReassortant VirusesSwineViral TropismVirus ReplicationCytokinesex vivoinfluenzainnate host responsesrisk assessmentswine influenzatropism

Identifiers

PMID40742730
PMCPMC12313140

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.