Nodular morphea on the breast of a pregnant woman-case report and literature review.

Omnia Mohamed Naguib Gaghous, Mohamed Samir Abd El Aziz Ismael, Mohamed Khaled Selim, Ayman Abdelmaksoud, Uwe Wollina, Abdulkarim Hasan, Ibtisam Al Hajj

Abstract readCase ReportsReview

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Review in Wiener medizinische Wochenschrift (1946), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

7 authors.

Omnia Mohamed Naguib GaghousDepartment of Dermatology, Alsadiq Hospital, Saihat, Saudi Arabia.ORCID http://orcid.org/0009-0000-6155-4355

Mohamed Samir Abd El Aziz IsmaelDepartment of Dermatology, El-Sinbelaween Hospital, Mansoura, Egypt.ORCID http://orcid.org/0000-0001-9702-5017

Mohamed Khaled SelimDepartment of Dermatology, Faculty of Medicine, Mansoura University, Mansoura, Egypt.ORCID http://orcid.org/0000-0003-4208-7426

Ayman AbdelmaksoudMansoura Dermatology, Venerology and Leprology Hospital, Amien Alsamanoudy Street, from Abdelsalam Aaref Street, Mansoura, Egypt. behcet.behcet@yahoo.com.ORCID http://orcid.org/0000-0003-4848-959X

Uwe WollinaFormer head of Department of Dermatology and Allergology, Städtisches Klinikum Dresden, Academic Teaching Hospital, Dresden, Germany.ORCID http://orcid.org/0000-0001-5933-2913

Abdulkarim HasanDepartment of Pathology, Faculty of Medicine, Al-Azhar University, Cairo, Egypt.ORCID http://orcid.org/0000-0003-0391-306X

Ibtisam Al HajjDepartment of Dermatology, Kuwait University Hospital, Sana'a, Yemen.ORCID http://orcid.org/0009-0008-6810-5008

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nodular lesions on the breast can be alarming for women and have a negative physical and psychological impact. The lesions might be underdiagnosed as keloid or overdiagnosed as malignancies. To reach an accurate diagnosis, pathological examination is required. We herein present a case of linear keloidal morphea on the breast of a 30-year-old woman who presented with a firm asymptomatic lesion that developed during pregnancy. She had a family history of autoimmune diseases. Careful clinical and dermoscopic investigations with histopathological examination were consistent with nodular morphea. In addition, we analyze reports of nodular morphea from the past 25 years. The most common comorbidities of nodular morphea are systemic sclerosis, systemic lupus erythematosus, and morphea (localized scleroderma). Treatment is a challenge.

Indexed as

Breast DiseasesPregnancy ComplicationsScleroderma, LocalizedAdultBreastDermoscopyDiagnosis, DifferentialFemaleHumansKeloidPregnancySkinComorbiditiesHistopathologyNodular morpheaSystemic sclerosisTreatment

Identifiers

PMID40742658

DOI10.1007/s10354-025-01098-4

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.