ArticleThe international journal of cardiovascular imaging2025
A prognostically meaningful definition of non-dilated left ventricular cardiomyopathy.
Article in The international journal of cardiovascular imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Non-Dilated Left Ventricular Cardiomyopathy: Exploring the Spectrum from Phenotype to Disease Entity.Journal of clinical medicine · 2026Review
- Non-Dilated Left Ventricular Cardiomyopathy (NDLVC): A Name, Multiple Souls.Current cardiology reports · 2026Review
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Authors and funding
18 authors.
Funding
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Abstract
Non-dilated left ventricular cardiomyopathy (NDLVC) has been defined as non-ischemic LV scarring and/or fatty replacement and/or hypokinesia, without LV dilation. We tried to identify specific criteria for LV dilation and dysfunction to implement this definition. We identified all non-ischemic cardiomyopathy patients undergoing a cardiovascular magnetic resonance scan from 2012 to 2022 with LV ejection fraction (LVEF) < 55% and/or non-ischemic late gadolinium enhancement (LGE) and/or fatty replacement, and without specific etiologies. The primary endpoint was a composite of all-cause death, sustained ventricular tachycardia or fibrillation. The cohort included 388 patients (32% women, median age 55 years [interquartile range 43-63]). Over 4.3 years (1.9-7.0), 59 patients (15%) developed a primary endpoint event. The risk increased exponentially with LVEDVi values, with inflection points approaching the upper reference limit of LVEDVi (< 96 mL/m
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