Evidence map›Paper›PMID 40742610›Full record

ArticleMycopathologia2025

Acute Respiratory Distress Syndrome Due to COVID-19-Associated Pulmonary Aspergillosis with Rare Extensive Tracheobronchial Pseudomembranous Involvement: A Case Report.

Liu He, Wei Wang, Danyan Cai, Xiaoshan Zhang, Xinyuan Tan

Abstract readCase Reports
In one paragraph

Article in Mycopathologia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Liu HeDepartment of Infectious Diseases and Public Health, City University of Hong Kong, Hong Kong, 999077, China.
Wei WangPCCM, Chongqing Traditional Chinese Medicine Hospital, Chongqing, 400021, China.
Danyan CaiPCCM, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, 510120, China.
Xiaoshan ZhangPCCM, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, 510120, China.
Xinyuan TanPCCM, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, 510120, China. tantcm007@163.com.ORCID http://orcid.org/0000-0002-6675-7220

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

COVID-19-associated pulmonary aspergillosis (CAPA) significantly exacerbates the clinical outcomes of COVID-19 patients, contributing to heightened mortality. Aspergillus tracheobronchitis, a manifestation of invasive pulmonary aspergillosis, specifically involves the tracheobronchial tree. According to the 2020 European Confederation of Medical Mycology/International Society for Human and Animal Mycology (ECMM/ISHAM) consensus criteria, airway biopsy via bronchoscopy is the definitive method for CAPA diagnosis, underscoring its critical role in the management of COVID-19 patients. This case report describes an elderly male patient with COVID-19 who presented with extensive pseudomembranous involvement of the tracheobronchial tree, identified through bronchoscopy. The pseudomembrane, spanning from the glottis to the bronchi and characterized by its yellow-white translucency, was removed. Subsequent pathological examination and next-generation sequencing confirmed an Aspergillus infection. Despite the initiation of antifungal therapy, the patient's condition deteriorated, leading to his death.

Indexed as

COVID-19Invasive Pulmonary AspergillosisPulmonary AspergillosisRespiratory Distress SyndromeAgedAntifungal AgentsBronchoscopyFatal OutcomeHumansMaleSARS-CoV-2Antifungal AgentsAcute respiratory distress syndromeAspergillus tracheobronchitisCase reportCOVID-19-associated pulmonary aspergillosisExtensive tracheobronchial pseudomembraneFungal infectionPseudomembranous Aspergillus tracheobronchitis

Identifiers

PMID40742610
PMCPMC12313819

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.