Evidence map›Paper›PMID 40742535›Full record

ArticleAnalytical and bioanalytical chemistry2025

Development of an immunoassay lollipop using syringe-autoinjected visual distance readout for point-of-care testing.

Cuili Li, Maojie Xiang, Jie Liu, Shuting Zhang, Haojie Li, Guanglei Fu

Abstract read
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In one paragraph

Article in Analytical and bioanalytical chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Cuili LiSchool of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation, Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Yantai University, Yantai, 264005, Shandong, China.
Maojie XiangSchool of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation, Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Yantai University, Yantai, 264005, Shandong, China.
Jie LiuDepartment of Clinical Laboratory, Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai, 264000, Shandong, China.
Shuting ZhangSchool of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation, Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Yantai University, Yantai, 264005, Shandong, China.
Haojie LiSchool of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation, Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Yantai University, Yantai, 264005, Shandong, China.
Guanglei FuSchool of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation, Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Yantai University, Yantai, 264005, Shandong, China. fuguanglei@ytu.edu.cn.

Funding

Natural Science Foundation of Shandong Province ZR2024MH055Research Starting Foundation of Yantai University 2222006
6 · The paper itself

Abstract

Pressure-based detection has drawn increasing interest for developing immunoassays but is still challenged in point-of-care testing (POCT). In this work, a pressure-based immunoassay "lollipop" was developed using syringe-autoinjected visual distance readout. The "lollipop" consisted of a disposable syringe "stick" as the immuno-recognition host and a chip "head" as the signal readout element. Using urinary microalbuminuria (mALB) as a model target, we constructed the immunoassay system on the interior cylinder surface of the syringe. In the presence of H

Indexed as

AlbuminuriaPoint-of-Care TestingSyringesEquipment DesignHumansImmunoassayLimit of DetectionMetal NanoparticlesPlatinumPlatinumDistance readoutImmunoassaysLollipopsSyringesUrinary microalbuminuria

Identifiers

PMID40742535

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.