Evidence map›Paper›PMID 40742450›Full record

ArticleBioprocess and biosystems engineering2025

Clitoria ternatea flower extract assisted synthesis of Pluronic F127 and L-histidine coated SrO

Aakash Sharma, Suhas Ballal, Deeplata Sharma, Jaivik Pathak, AbdulAziz A AlGhamdi, Srinivas Tadepalli, Indumathi Thangavelu

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Article in Bioprocess and biosystems engineering, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Aakash SharmaCentre of Research Impact and Outcome, Chitkara University, 140417, Rajpura, Punjab, India.
Suhas BallalDepartment of Chemistry and Biochemistry, JAIN (Deemed-to-Be University), Bangalore, 560069, Karnataka, India.
Deeplata SharmaDepartment of Sciences, Vivekananda Global University, Jaipur, 303012, India.
Jaivik PathakDepartment of Applied Science, PIT, Parul University, Vadodara, Gujarat, 391760, India.
AbdulAziz A AlGhamdiDepartment of Chemical Engineering, College of Engineering, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, 11432, Kingdom of Saudi Arabia.
Srinivas TadepalliDepartment of Chemical Engineering, College of Engineering, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, 11432, Kingdom of Saudi Arabia. stadepalli@imamu.edu.sa.
Indumathi ThangaveluDepartment of Chemistry, CHRIST (Deemed to Be University), Bangalore, Karnataka, 560029, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatocellular carcinoma (HepG2) is a highly aggressive liver cancer with poor prognosis, limited treatment options, and high mortality rates, making it a serious global health concern that demands urgent development of more effective and safer therapeutic approaches. In this context, the present study focuses on the green synthesis of SrO2 nanoparticles using Clitoria ternatea flower extract, followed by surface modification with Pluronic F127 (PF127) and L-histidine (LH), to fabricate SrO2-PF127-LH nanocomposites aimed at evaluating their potential anticancer efficacy against the HepG2 cell line. Various analytical techniques were used to characterize the nanocomposite, and then their anticancer activity against HePG2 liver cancer cells, antioxidant properties, and antimicrobial activity against the bacteria mentioned above were evaluated. XRD revealed the crystalline nature of SrO

Indexed as

Anti-Infective AgentsAntineoplastic AgentsAntioxidantsFlowersHistidineNanocompositesPlant ExtractsPoloxamerAnti-Bacterial AgentsHep G2 CellsHumansLiver NeoplasmsAnti-Bacterial AgentsAnti-Infective AgentsAntineoplastic AgentsAntioxidantsHistidinePlant ExtractsPoloxamerAntimicrobial activityAntioxidant activityClitoria ternatea extractHePG2 liver cancerl-histidinePluronic F127Reactive oxygen species (ROS)SrO₂ nanoparticles

Identifiers

PMID40742450

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.