ArticleAnnals of medicine2025
The impact of preoperative biliary drainage on bile colonization of patients undergoing pancreaticoduodenectomy.
Article in Annals of medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Tumor Location and Preoperative Biliary Stenting Shape Gut Microbiome Diversity in Pancreatic Cancer.Cancers · 2026Article
- Impact of fungal biliary colonization on postoperative outcomes following pancreaticoduodenectomy: A systematic review.Pakistan journal of medical sciences · 2026Review
- Should Preoperative Biliary Decontamination Be Considered to Minimize Morbidity and Mortality Following Pancreatoduodenectomy?Antibiotics (Basel, Switzerland) · 2026Article
- Clinical application of targeted next-generation sequencing in detecting organ/space surgical site infection in patients following biliary-pancreatic surgery.Frontiers in microbiology · 2026Article
- Epidemiology and Management of Postoperative Infections in Hepatectomy and Pancreaticoduodenectomy.Journal of surgery and research · 2025Article
Corrections and comments
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Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPreoperative biliary drainage (PBD) may be performed for jaundiced patients with periampullary tumors. This study aimed to evaluate the impact of PBD on biliary microbiome and perioperative complications in patients undergoing pancreaticoduodenectomy (PD).
methodsThis retrospective study enrolled 323 patients who underwent PD between March 2018 and March 2024. Intraoperative bile specimens were obtained for microbiological analysis of species identification and antimicrobial resistance patterns..
resultsPBD was performed in 191 (59.1%) of the 323 patients. Organ/space surgical site infection (SSI) (51.8% vs 37.9%,
conclusionsThere were fundamental differences in the bile microbiome profile and antibiotic resistance of patients with/without PBD. These findings suggest that adjusting perioperative antibiotic regimens based on biliary culture may be warranted.
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