Evidence map›Paper›PMID 40742132›Full record

ArticleJournal of virology2025

Anellovirus constraint from 2 to 6 months postpartum followed by betatorquevirus and gammatorquevirus dominance in serum and milk.

Anne L Timmerman, Antonia L M Schönert, Martin Deijs, Jacqueline van Rijswijk, Marit J van Gils, Johannes B van Goudoever, Britt J van Keulen, Lia van der Hoek

Abstract read
In one paragraph

Article in Journal of virology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Anne L TimmermanLaboratory of Experimental Virology, Department of Medical Microbiology and Infection Prevention, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.ORCID 0000-0002-8015-9542
Antonia L M SchönertLaboratory of Experimental Virology, Department of Medical Microbiology and Infection Prevention, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
Martin DeijsLaboratory of Experimental Virology, Department of Medical Microbiology and Infection Prevention, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
Jacqueline van RijswijkLaboratory of Experimental Virology, Department of Medical Microbiology and Infection Prevention, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
Marit J van GilsLaboratory of Experimental Virology, Department of Medical Microbiology and Infection Prevention, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.ORCID 0000-0003-3422-8161
Johannes B van GoudoeverDepartment of Pediatrics, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.ORCID 0000-0003-3960-1703
Britt J van KeulenDepartment of Pediatrics, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.ORCID 0000-0003-2848-9533
Lia van der HoekLaboratory of Experimental Virology, Department of Medical Microbiology and Infection Prevention, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.ORCID 0000-0003-2803-642X

Funding

Universiteit van Amsterdam 24175
6 · The paper itself

Abstract

Anelloviruses are ubiquitous, diverse viruses in the human virome not causing disease. In adults, the anellovirus composition (anellome) is dominated by alphatorqueviruses. However, infants seem to acquire their first anellovirus infections beginning with beta IMPORTANCE: Anelloviruses are omnipresent in the human population, yet their transmission routes, especially in early life, remain unclear. This study focused on compartmentalization between blood and the mammary gland to investigate the likelihood of virus transmission via milk. We show that serum and milk samples generally share anellovirus genera and lineages. Interestingly, serum as well as milk samples collected between 2 and 6 months postpartum tested mainly negative for anelloviruses, but those received thereafter were dominated by beta- and gammatorquevirus, reflecting the initial anellovirus colonizers observed in children.

Indexed as

AnelloviridaeDNA Virus InfectionsMilk, HumanSerumAdultFemaleHumansInfantLactationPhylogenyPostpartum PeriodViral LoadViromealphatorquevirusanellovirusbetatorqueviruscolonizationcompartmentalizationgammatorquevirushuman milkTTV

Identifiers

PMID40742132
PMCPMC12363169

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.