Evidence map›Paper›PMID 40741950›Full record

ArticleAntimicrobial agents and chemotherapy2025

Fractional curative killing of pyronaridine or artesunate combinations with tafenoquine, 4-aminoquinolines, or azithromycin in a murine malaria-luciferase model.

Gayoung Lee, Janessa Sochima Aneke, David J Sullivan

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Gayoung LeeW. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
Janessa Sochima AnekeW. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
David J SullivanW. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.ORCID 0000-0003-0319-0578

Funding

Optimized Combination Antimalarial Drug TherapyR01AI111962 · NIAID · GEORGETOWN UNIVERSITY · PI ROEPE, PAUL D., SULLIVAN, DAVID JOSEPH · 2014 to 2018
$4.9M
Bloomberg PhilanthropiesNational Institute of Allergy and Infectious Diseases RO1 AI111962NIAID NIH HHS R01 AI111962
6 · The paper itself

Abstract

Malaria drug interactions in cytostatic or inhibitory

Indexed as

AminoquinolinesAntimalarialsArtemisininsAzithromycinBenzoxazolesMalariaNaphthyridinesPlasmodium bergheiAmodiaquineAnimalsArtesunateChloroquineDisease Models, AnimalDrug Therapy, CombinationFemaleHalf-LifeAminoquinolinesAmodiaquineAntimalarialsArtemisininsArtesunateAzithromycinBenzoxazolesChloroquineNaphthyridinespyronaridinetafenoquineamodiaquineartemisinin tafenoquineazithromycinchloroquinecombination chemotherapymalariaPlasmodiumpyronaridine

Identifiers

PMID40741950
PMCPMC12406666

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.