Evidence map›Paper›PMID 40741771›Full record

ReviewCytoskeleton (Hoboken, N.J.)2026

The Role of Microfilaments in Cilia Formation and Function.

Qian Lyu, Mingming Ma, Ting Song

Abstract readReview
In one paragraph

Review in Cytoskeleton (Hoboken, N.J.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Qian LyuCenter for Cell Structure and Function, Shandong Provincial Key Laboratory of Animal Resistance Biology, College of Life Sciences, Shandong Normal University, Jinan, China.
Mingming MaCenter for Cell Structure and Function, Shandong Provincial Key Laboratory of Animal Resistance Biology, College of Life Sciences, Shandong Normal University, Jinan, China.
Ting SongCenter for Cell Structure and Function, Shandong Provincial Key Laboratory of Animal Resistance Biology, College of Life Sciences, Shandong Normal University, Jinan, China.ORCID https://orcid.org/0000-0001-5945-6676

Funding

National Natural Science Foundation of China 32300694Natural Science Foundation of Shandong Province ZR2024QC038
6 · The paper itself

Abstract

Cilia are microtubule-based, highly specialized organelles that are indispensable for tissue and organ development. Failures in ciliogenesis underlie severe genetic disorders known as ciliopathies. Microfilaments, a major cytoskeletal component, maintain cell architecture and facilitate motility. Microfilaments are formed by the polymerization of actin. Actin not only regulates basal-body migration and docking at the plasma membrane but also interacts with motor proteins that mediate vesicular trafficking. Furthermore, remodeling of the actin lattice modulates microtubule growth and organization. In recent years, the contribution of microfilaments to ciliogenesis and ciliary homeostasis has garnered increasing interest. This review summarizes the regulatory mechanisms underlying actin cytoskeleton dynamics in ciliogenesis, ciliary elongation, and ciliary stability over recent years.

Indexed as

Actin CytoskeletonCiliaActinsAnimalsHumansActins

Identifiers

PMID40741771
PMCPMC13485226

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.