ArticleCureus2025
A Retrospective Single-Center Cohort Study on Heme Transfusions in Orthopedic Surgeries.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Blood transfusions remain a critical yet potentially hazardous intervention in orthopedic surgical procedures, particularly those associated with substantial blood loss such as joint arthroplasties, spinal surgeries, and complex trauma reconstructions. This retrospective cohort study, conducted at RL Jalappa Hospital, Kolar, India, from February 2023 to January 2024, comprehensively evaluated transfusion practices across 395 major orthopedic surgeries. The study revealed an overall transfusion rate of 10.3%, with significant variation across procedure types, ranging from 6.8% in elective arthroplasties to 18.2% in revision surgeries and 22.4% in complex spinal procedures. Multivariate analysis identified several independent predictors of transfusion requirements, including advanced age (>65 years, OR 2.4), preoperative anemia (Hb <10 g/dL, OR 3.2), prolonged surgical duration (>3 hours, OR 2.1), and substantial intraoperative blood loss (>500 mL, OR 4.0). Importantly, transfused patients demonstrated significantly worse clinical outcomes, including extended hospital stays (7.2 vs 4.5 days, p<0.001), higher complication rates (24% vs 8%, p=0.003), particularly surgical site infections (12% vs 4%), and increased 30-day readmission rates (8% vs 3%, p=0.02). The study also evaluated institutional transfusion triggers, finding considerable variability from recommended guidelines, with 42% of transfusions administered at hemoglobin levels of >8 g/dL in hemodynamically stable patients. These findings underscore the urgent need for standardized, evidence-based transfusion protocols, comprehensive preoperative optimization strategies, and robust blood management programs in orthopedic surgery. The study provides a framework for developing institution-specific guidelines to minimize unnecessary transfusions while optimizing patient outcomes and resource utilization.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.