ArticleCureus2025
Pheochromocytoma Associated With Neurofibromatosis Type 1: A Case Report.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We report a complex case of pheochromocytoma in a 50-year-old woman with a longstanding diagnosis of neurofibromatosis type 1 (NF-1), characterized by multiple cutaneous neurofibromas and axillary freckling. NF-1 is an autosomal dominant disorder that infrequently presents with pheochromocytoma, a potentially life-threatening endocrine tumor. The patient's clinical presentation included recurrent abdominal pain, unintentional weight loss, and poorly controlled hypertension despite longstanding antihypertensive treatment and management of type 2 diabetes mellitus. What makes this case unique is the size of the tumor (10 cm), the initial misinterpretation as a renal mass, and the delay in diagnosis despite classical symptoms. Diagnostic workup revealed a palpable right renal mass, with ultrasound and computed tomography confirming a large adrenal mass. Elevated urinary metanephrines established the diagnosis of pheochromocytoma. This case underscores the necessity for clinicians to maintain a high index of suspicion for pheochromocytoma in patients with NF-1 and hypertensive symptoms to enable timely intervention and prevent severe complications.
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