Evidence map›Paper›PMID 40741526›Full record

ArticleJournal of diabetes and metabolic disorders2025

Association and haplotype analysis of TCF7L2 gene variants with development of obesity in type 2 diabetic patients among Northern Iranians.

Saima Abbaspour, Parvaneh Keshavarz, Alireza Sharafshah

Abstract read
In one paragraph

Article in Journal of diabetes and metabolic disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Saima AbbaspourSchool of Medicine, Guilan University of Medical Sciences, Rasht, Iran.
Parvaneh KeshavarzCellular and Molecular Research Center, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran.
Alireza SharafshahCellular and Molecular Research Center, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The current study aimed to investigate the possible association of Materials and methods: DNA extraction from whole blood of all subjects was done by salting-out technique. A total of 483 T2DM patients (307 T2DM individuals without Obesity and 176 T2DM individuals with Obesity) were genotyped through TaqMan assay technology. Statistical analyses were computed by ASSOTEST, Haploview (ver. 4.2), SPSS (ver. 27), and Python (ver. 3.13). Results: Clinical characteristics assessments between the study groups showed that there was significant association for the gender type of T2DM individuals for being obese ( Conclusion: In conclusion, this study indicated various significant results highlighting on the association of rs7903146 with susceptibility to obesity among northern Iranians with T2DM. Importantly, this study showed that females are more at risk of getting obesity than males. Supplementary Information: The online version contains supplementary material available at 10.1007/s40200-025-01658-w.

Indexed as

Obesityrs7903146TCF7L2 geneType 2 diabetesVariant

Identifiers

PMID40741526
PMCPMC12304359

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.