ArticleCancer management and research2025
Hypopharyngeal Squamous Cell Carcinoma in Elderly Patients Aged ≥70 Years: Surgery and Postoperative Radiotherapy Improves Outcomes in Selected Patients.
Article in Cancer management and research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Efficacy and Safety of Induction Chemotherapy Followed by Concurrent Chemoradiotherapy in Locoregionally Advanced Hypopharyngeal Carcinoma.Advances in radiation oncology · 2026Article
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5 authors.
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Abstract
Objective: To summarize the efficacy of surgery plus postoperative radiotherapy as initial treatment in elderly patients aged ≥70 years with advanced hypopharyngeal cancer and to analyze prognostic factors. Methods: Retrospective analysis of 77 elderly patients aged ≥70 years with stage III-IV hypopharyngeal squamous cell carcinoma who underwent surgery as initial treatment at Shandong Provincial ENT Hospital between 2006-2020. Treatment completion rate and prognostic factors were summarized and analyzed, with comparisons made to non-surgical treatments in published literature. SPSS 26.0 was used for analysis. Univariate Cox regression analysis was applied to identify potential predictors of overall survival (OS) and disease-free survival (DFS). Kaplan-Meier method with Log rank test was used to calculate and compare survival rates. Multivariate analysis employed the Cox proportional hazards regression model, with Results: The study achieved 100% follow-up with a median duration of 62 months. Among the cohort, 26 patients received surgery only whilst 51 received surgery plus radiotherapy, seven patients failed to complete radiotherapy resulting in a completion rate of 86.27%. Survival analysis revealed significant intergroup differences: at 1 year, OS/DFS rates were 76.9%/73.1% in Group A versus 93.2%/81.8% in Group B (both Conclusion: Elderly hypopharyngeal cancer patients tolerated surgery and postoperative radiotherapy well. Active pursuit of comprehensive treatment is recommended for fit stage III-IV patients aged ≥70 years to improve outcomes.
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