ArticleArchives of medical science : AMS2025
Risk factors of severe course and fatality in children hospitalized for COVID-19: a two-center cohort study.
Article in Archives of medical science : AMS, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Introduction: After 3 years of the pandemic, predictors of COVID-19 severity in children are still not completely known. This study was designed to define the high-risk group in hospitalized children. Material and methods: The analysis covered 2338 children in two centers. Among patients with a severe course, three groups were identified: requiring and not requiring mechanical ventilation, and those who died. Results: The median age of 70 children (54% female) with severe COVID-19 was 32 months. In 43 (61%) children, comorbidities were present. No one was vaccinated against COVID-19. On admission, medium SpO Conclusions: Risk factors for a severe course of COVID-19 were: young age, lack of COVID-19 vaccination, auscultation changes and dyspnea at admission. The presence of comorbidities, high CRP, LDH, and ferritin levels were the predictors of need for mechanical ventilation and death. Among children mechanically ventilated, teenagers generally had a favorable prognosis of recovery, whereas infants with comorbidities were at the highest risk of death.
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