ArticleChemistry of materials : a publication of the American Chemical Society2023
Harnessing the Materials Chemistry of Mesoporous Silicon Nanoparticles to Prepare "Armor-Clad" Enzymes.
Article in Chemistry of materials : a publication of the American Chemical Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Engineering a Mesoporous Silicon Nanoparticle Cage to Enhance Performance of a Phosphotriesterase Enzyme for Degradation of VX Nerve Agent.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
There is a growing interest in nanomaterials that can encapsulate enzymes while retaining their ability to function within the confines of a nanocage. Here porous silicon nanoparticles (pSiNPs) are evaluated as an enzyme cage, utilizing the aqueous chemistry of silicon to dynamically restructure the mesopore structure, immobilizing, and confining the enzyme. The common bioluminescent reporter enzyme nanoluciferase (Nluc) is used to evaluate two different trapping chemistries, and impacts on the stability and catalytic performance of the enzyme are compared with controls involving free enzyme and enzyme electrostatically adsorbed to a pSiNP host without the use of trapping chemistry. The two chemistries exploited in this study are (1) oxidative trapping, where mild aqueous oxidation of the elemental silicon skeleton in the mesoporous silicon host swells and restructures the pore walls, physically trapping the Nluc payload in a porous SiO
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Registered trials
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