Evidence map›Paper›PMID 40741114›Full record

ArticleClinical case reports2025

ST Elevation in aVR: An Atypical Presentation of Pulmonary Embolism.

Bernard R Francis, Nouman Arshad, Mohammad El-Din, Ibrahim Antoun

Abstract read
In one paragraph

Article in Clinical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Bernard R FrancisDepartment of Cardiology Kettering General Hospital Kettering UK.
Nouman ArshadDepartment of Cardiology Kettering General Hospital Kettering UK.
Mohammad El-DinDepartment of Cardiology Kettering General Hospital Kettering UK.
Ibrahim AntounDepartment of Cardiology Kettering General Hospital Kettering UK.ORCID https://orcid.org/0009-0003-8177-3047

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ST elevation in aVR on the electrocardiogram (ECG) indicates high-risk acute coronary syndrome (ACS) but is rarely reported in pulmonary embolisms (PEs). We present a 47-year-old female with a history of PE and ankylosing spondylitis admitted for chest pain, nausea, and an episode of possible collapse. Her ECG showed ST elevation in aVR with anterolateral ST depressions, prompting a normal emergency coronary angiogram. Bedside echocardiography revealed right ventricular (RV) dilatation, and lab tests showed elevated D-dimer levels and troponin. Urgent computed tomography of the pulmonary arteries (CTPA) confirmed large bilateral PEs. The patient was treated with Enoxaparin and transitioned to Warfarin, resulting in symptom improvement. ST-segment elevation in lead aVR may mimic ACS but suggests significant conditions like PE, often from RV strain and impaired coronary blood flow due to acute RV failure. Clinicians should suspect PE in patients with aVR changes, especially with relevant clinical history and signs of RV pressure overload on echocardiography, to prevent misdiagnosis and ensure timely care.

Indexed as

aVRcoronary angiogramelectrocardiogrampulmonary embolismST elevation

Identifiers

PMID40741114
PMCPMC12307230

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.