SynthesisWorld journal of gastroenterology2025
Cardiovascular risk assessment and predictors of cardiac decompensation after transjugular intrahepatic portosystemic shunt in patients with cirrhosis.
Synthesis in World journal of gastroenterology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Long-term cardiac remodeling after transjugular intrahepatic portosystemic shunt placement: a cardiac MRI study.European radiology · 2026Article
- Navigating TIPS in the era of ageing and metabolic comorbidity: a contemporary narrative review of risk, resilience, and outcomes.Gastroenterology report · 2026Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPortal hypertension (PH) is a major complication of chronic liver disease and a leading cause of mortality and morbidity in patients with cirrhosis. Transjugular intrahepatic portosystemic shunt (TIPS) is an established treatment for PH-related complications, including refractory ascites, variceal bleeding, hepatic hydrothorax and Budd-Chiari syndrome. However, post-TIPS cardiac decompensation has been reported in up to 25% of patients, often due to haemodynamic shifts revealing occult cardiac dysfunction. Current approaches to pre-procedural cardiac assessment and risk stratification remain inconsistent. This systematic review examines current recommendations and emerging strategies for cardiovascular evaluation in patients with cirrhosis prior to a TIPS.
aimTo identify the key predictive factors for cardiac decompensation following a TIPS in patients with cirrhosis.
methodsA systematic review of available literature, using PubMed (including MEDLINE), Embase and Cochrane databases. Results were searched comprehensively, without exclusion criteria, from inception to May 2025. Given the predominance of retrospective cohort studies, risk of bias assessment was primarily performed using the ROBINS-E tool.
resultsThirteen studies were included (
conclusionMultiple predictors of cardiac decompensation following TIPS exist, however studies are of limited quality. Implementing reliable markers may enable early risk stratification, candidate selection and guide pre-procedural optimisation.
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Registered trials
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