Evidence map›Paper›PMID 40740931›Full record

ArticleWorld journal of gastrointestinal surgery2025

Ice-breaking sign: A radiological sign influencing the treatment strategies for choledocholithiasis.

Xiao-Yu Zhao, Ming Chen, Gang Wang, Long Cui, Zhi Xu, Chun-Sheng Hou, Li-Xin Wang, Ling-Fu Zhang, Xiao-Feng Ling

Abstract read
In one paragraph

Article in World journal of gastrointestinal surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xiao-Yu ZhaoDepartment of General Surgery, Peking University Third Hospital, Beijing 100191, China.
Ming ChenDepartment of Radiology, Peking University Third Hospital, Beijing 100191, China.
Gang WangDepartment of General Surgery, Peking University Third Hospital, Beijing 100191, China.
Long CuiDepartment of General Surgery, Peking University Third Hospital, Beijing 100191, China.
Zhi XuDepartment of General Surgery, Peking University Third Hospital, Beijing 100191, China.
Chun-Sheng HouDepartment of General Surgery, Peking University Third Hospital, Beijing 100191, China.
Li-Xin WangDepartment of General Surgery, Peking University Third Hospital, Beijing 100191, China.
Ling-Fu ZhangDepartment of General Surgery, Peking University Third Hospital, Beijing 100191, China.
Xiao-Feng LingDepartment of General Surgery, Peking University Third Hospital, Beijing 100191, China. xiaofengling@bjmu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCholedocholithiasis is a common benign disease of the biliary tract. We identified a particular type of choledocholithiasis characterized by sudden narrowing of the common bile duct at the site of impaction, which caused a marked increase in surgical difficulty and risk compared to treatment for typical choledocholithiasis. This phenomenon has not been described in previous studies.

aimTo propose the ice-breaking sign and evaluate its influence on treatment strategies for choledocholithiasis.

methodsUsing a retrospective case-control study design, patients who were diagnosed with common bile duct stones and admitted to the Emergency Department of Peking University Third Hospital between January 2018 and December 2023 were included. Propensity score matching was used to match cases and controls. Univariate analysis was conducted to assess the differences in clinical data between the two groups of patients.

resultsThere were no significant differences in the baseline data between the two groups, except for higher incidence of jaundice, alkaline phosphatase and total bilirubin in the ice-breaking sign group. Compared to the control group, the ice-breaking sign group had lower success rates for endoscopic retrograde cholangiopancreatography (25.0%

conclusionThe ice-breaking sign, a newly identified radiological phenomenon, may influence therapeutic decisions in choledocholithiasis, suggesting laparoscopic common bile duct exploration as the preferred approach over endoscopic retrograde cholangiopancreatography in patients exhibiting this sign.

Indexed as

CholedocholithiasisDifficult common bile duct stonesEndoscopic managementLaparoscopic managementSurgical approach

Identifiers

PMID40740931
PMCPMC12305235

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.