ArticleFrontiers in pediatrics2025
Identifying the need for surgical intervention in pediatric bacterial meningitis: single-center experience.
Article in Frontiers in pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Intracranial complications of bacterial meningitis can arise at any stage and may necessitate neurosurgical intervention. This study evaluates clinical, laboratory, and imaging findings predictive of surgical need in these cases. Methods: Between 2013 and 2023, 52 pediatric patients with severe neurological symptoms due to bacterial meningitis were admitted to PICU at Van Training and Research Hospital. Patients were classified into two groups: those with intracranial complications (Group 1, Results: Among 52 patients (67.3% male, mean age 76.7 ± 72.0 months), 36 (69.2%) developed intracranial complications, and 9 (17.3%) required surgery. CRP levels were significantly higher in Group 1B (226 mg/dl) than in Group 1A (63 mg/dl) ( Conclusion: CRP >150 mg/dl, CSF glucose <6.75 mg/dl, and protein/glucose ratio >18.9 indicate high surgical risk. MRI is recommended for localization, with early neurosurgical consultation and multidisciplinary management for cases with single-area empyema.
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