ArticleJournal of the anus, rectum and colon2025
Investigation of Peritoneal Lavage Cytology before and after Tumor Resection as a Prognostic Factor in Colorectal Cancer.
Article in Journal of the anus, rectum and colon, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objectives: There is no consensus on the significance of peritoneal lavage cytology for the prognosis of patients with colorectal cancer. In this prospective multicenter study, we aimed to determine whether positive peritoneal lavage cytology results predict poor patient outcomes and to clarify if the appropriate timing of cytology is before or after tumor resection. Methods: Patients diagnosed with pathological stage II or III colorectal cancer between 2013 and 2017 were enrolled in this study. Peritoneal lavage cytology was performed twice, before and after the tumor resection, and the results were analyzed to determine their effect on prognosis and peritoneal recurrence. Results: We analyzed 1378 patients, and 54 (3.9%) had positive cytology results. Furthermore, 30 patients were positive before tumor resection, 13 after tumor resection, and 11 for both markers. The 5-year relapse-free survival rates (5yRFS) with positive and negative cytology before tumor resection in patients with pStage II were 44.4 and 81.7%, respectively (p=0.0014). The 5-year overall survival rates (5yOS) were 57.1 and 91.6%, respectively (p=0.0046). In Stage III, the 5yRFS and 5yOS between patients with positive and negative cytology did not differ. Patients with positive and negative cytology before tumor resection in pStage II had peritoneal recurrence rates of 11.1 and 1.66%, respectively (p=0.034). These rates were 12.5 and 2.51%, respectively, in patients with pStage III (p=0.011). Conclusions: A positive cytology result before tumor resection is a prognostic factor in Stage II colorectal cancer and is instrumental in predicting peritoneal recurrence in Stages II and III colorectal cancer.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.