Evidence map›Paper›PMID 40740708›Full record

ArticleRoyal Society open science2025

Tissue-specific metabolomic signatures for a

Rene Coig, Benjamin Harrison, Richard Johnson, Michael J MacCoss, Daniel Promislow

Abstract read
In one paragraph

Article in Royal Society open science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Tissue-specific metabolomic signatures for aRoyal Society open science · 2025
    Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Rene CoigDepartment of Laboratory Medicine and Pathology, University of Washington School of Medicine, Seattle, WA, USA.
Benjamin HarrisonDepartment of Laboratory Medicine and Pathology, University of Washington School of Medicine, Seattle, WA, USA.
Richard JohnsonDepartment of Genome Sciences, University of Washington, Seattle, WA, USA.
Michael J MacCossDepartment of Genome Sciences, University of Washington, Seattle, WA, USA.
Daniel PromislowJean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA, USA.ORCID https://orcid.org/0000-0001-7088-4495

Funding

University of Washington Nathan Shock Center of Excellence in the Basic Biology of AgingP30AG013280 · NIA · UNIVERSITY OF WASHINGTON · PI Maitreya J Dunham · 1995 to 2026
$27.1M
Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Annette L. Parks · 2014 to 2026
$13.5M
A systems biology approach to explain sex differences in agingR21AG074495 · NIA · UNIVERSITY OF WASHINGTON · PI PROMISLOW, DANIEL EDWARD · 2022 to 2023
$427k
NIA NIH HHS P30 AG013280NIA NIH HHS R21 AG074495NIH HHS P40 OD018537
6 · The paper itself

Abstract

Sex has a major effect on the metabolome. However, we do not yet understand the degree to which differences in metabolism are associated with anatomical dimorphism and modulated by sex-specific tissues. In the fruit fly,

Indexed as

DoublesexDrosophila melanogastermetabolomicssex differencessexual dimorphism

Identifiers

PMID40740708
PMCPMC12308351

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.