Evidence map›Paper›PMID 40740621›Full record

ArticleJournal of human reproductive sciences

The Report on the Effect of White and Black Truffle Extracts on Rat Semen Parameters

Victoria Nikolaevna Shelkovnikova, Maria Egorovna Dmitrieva, Ekaterina Vladimirovna Malygina, Natalia Alexandrovna Imidoeva, Alexander Yurievich Belyshenko, Maria Mikhailovna Morgunova, Anfisa Alexandrovna Vlasova, Tamara Yurievna Telnova, Anna Alexandrovna Batalova, Olga Evgenievna Lipatova and 5 more

Abstract read
In one paragraph

Article in Journal of human reproductive sciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Victoria Nikolaevna ShelkovnikovaDepartment for Research and Development, Laboratory of Experimental Neurophysiology, Irkutsk State University, Irkutsk, Russia.
Maria Egorovna DmitrievaDepartment for Research and Development, Laboratory of Experimental Neurophysiology, Irkutsk State University, Irkutsk, Russia.
Ekaterina Vladimirovna MalyginaDepartment for Research and Development, Laboratory of Experimental Neurophysiology, Irkutsk State University, Irkutsk, Russia.
Natalia Alexandrovna ImidoevaDepartment for Research and Development, Laboratory of Experimental Neurophysiology, Irkutsk State University, Irkutsk, Russia.
Alexander Yurievich BelyshenkoDepartment for Research and Development, Laboratory of Experimental Neurophysiology, Irkutsk State University, Irkutsk, Russia.
Maria Mikhailovna MorgunovaDepartment for Research and Development, Laboratory of Experimental Neurophysiology, Irkutsk State University, Irkutsk, Russia.
Anfisa Alexandrovna VlasovaDepartment for Research and Development, Laboratory of Experimental Neurophysiology, Irkutsk State University, Irkutsk, Russia.
Tamara Yurievna TelnovaDepartment for Research and Development, Laboratory of Experimental Neurophysiology, Irkutsk State University, Irkutsk, Russia.
Anna Alexandrovna BatalovaDepartment for Research and Development, Laboratory of Experimental Neurophysiology, Irkutsk State University, Irkutsk, Russia.
Olga Evgenievna LipatovaDepartment for Research and Development, Laboratory of Experimental Neurophysiology, Irkutsk State University, Irkutsk, Russia.
Tatyana Nikolaevna VavilinaDepartment for Research and Development, Laboratory of Experimental Neurophysiology, Irkutsk State University, Irkutsk, Russia.
Angelika Sergeevna ListopadDepartment for Research and Development, Laboratory of Experimental Neurophysiology, Irkutsk State University, Irkutsk, Russia.
Olga Vladimirovna YurlovaIrkutsk State Medical University, Irkutsk, Russia.
Elena Igorevna MartynovaDepartment for Research and Development, Laboratory of Experimental Neurophysiology, Irkutsk State University, Irkutsk, Russia.
Denis Victorovich Axenov-GribanovDepartment for Research and Development, Laboratory of Experimental Neurophysiology, Irkutsk State University, Irkutsk, Russia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Truffle extracts possess the unique properties that make them potentially valuable for medicinal purposes. The use of truffles in reproductive medicine may be of particular interest for developing medications with both spermatozoa-activating and contraceptive effects. Aim: Our experiment evaluated the influence of extracts of white and black truffle mushrooms on rat spermatozoa. Settings and Design: Animal model. Materials and Methods: The study utilized 28 samples of wild truffle fruiting bodies. In the experiment, we used ejaculate from male Wistar rats ( Statistical Analysis Used: The methods should be adequately detailed or referenced to other work. The statistical processing was performed in the Past software (V4.03) using the ANOVA analysis of variance with the Mann-Whitney test. Differences between the mean values of the parameters were considered statistically significant at Results: Research has shown that extracts from black and white truffles related to Tuber sp. have a stimulating effect on spermatozoa. Curvilinear velocity and beat cross-frequency also increased by 48% and 50%, respectively. Linearity showed a significant increase by 56% and straightness by 48%. This could be useful in the development of drugs to enhance sperm activity and lifespan. In addition, extracts from black truffles have been found to have a negative impact on spermatozoa, which could be relevant for developing new contraceptive drugs. Conclusion: Our study demonstrated the influence of methanol extracts of Tuber sp. mushrooms on male gametes of rats

Indexed as

Biologically active compoundsinfertilityrat spermatozoareproductive potentialTuber sp.

Identifiers

PMID40740621
PMCPMC12306714

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.