Evidence map›Paper›PMID 40740497›Full record

ArticleiScience2025

An antibiotic derivative as a new potential tool in the prevention of hemolytic uremic syndrome.

Elisa Varrone, Luciano Consagra, Domenica Carnicelli, Elisabetta Galassi, Beatrice Munari, Elisa Porcellini, Marta Pluchino, Giorgia Rossi, Federico Parenti, Catia Barboni and 15 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Elisa VarroneDepartment of Medical and Surgical Sciences (DIMEC), University of Bologna, 40126 Bologna, Italy.
Luciano ConsagraDepartment of Medical and Surgical Sciences (DIMEC), University of Bologna, 40126 Bologna, Italy.
Domenica CarnicelliDepartment of Medical and Surgical Sciences (DIMEC), University of Bologna, 40126 Bologna, Italy.
Elisabetta GalassiDepartment of Medical and Surgical Sciences (DIMEC), University of Bologna, 40126 Bologna, Italy.
Beatrice MunariDepartment of Medical and Surgical Sciences (DIMEC), University of Bologna, 40126 Bologna, Italy.
Elisa PorcelliniDepartment of Medical and Surgical Sciences (DIMEC), University of Bologna, 40126 Bologna, Italy.
Marta PluchinoDepartment of Medical and Surgical Sciences (DIMEC), University of Bologna, 40126 Bologna, Italy.
Giorgia RossiDepartment of Medical and Surgical Sciences (DIMEC), University of Bologna, 40126 Bologna, Italy.
Federico ParentiDepartment of Medical and Surgical Sciences (DIMEC), University of Bologna, 40126 Bologna, Italy.
Catia BarboniDepartment of Veterinary Medical Sciences (DIMEVET), University of Bologna, Ozzano dell'Emilia, 40064 Bologna, Italy.
Barbara BrunettiDepartment of Veterinary Medical Sciences (DIMEVET), University of Bologna, Ozzano dell'Emilia, 40064 Bologna, Italy.
Francesca RicciIRCCS Azienda Ospedaliero-Universitaria di Bologna, 40138 Bologna, Italy.
Pier Luigi TazzariIRCCS Azienda Ospedaliero-Universitaria di Bologna, 40138 Bologna, Italy.
Francesco ManoliIstituto per la Sintesi Organica e la Fotoreattività, Consiglio Nazionale delle Ricerche, 40129 Bologna, Italy.
Ilse ManetIstituto per la Sintesi Organica e la Fotoreattività, Consiglio Nazionale delle Ricerche, 40129 Bologna, Italy.
Paola PateriniDepartment of Medical and Surgical Sciences (DIMEC), University of Bologna, 40126 Bologna, Italy.
Gianluca StorciIRCCS Azienda Ospedaliero-Universitaria di Bologna, 40138 Bologna, Italy.
Massimiliano BonafèDepartment of Medical and Surgical Sciences (DIMEC), University of Bologna, 40126 Bologna, Italy.
Alejandro HochkoepplerDepartment of Pharmacy and Biotechnology, University of Bologna, 40136 Bologna, Italy.
Anna ZaghiniDepartment of Veterinary Medical Sciences (DIMEVET), University of Bologna, Ozzano dell'Emilia, 40064 Bologna, Italy.
Stefano MorabitoEuropean Reference Laboratory for Escherichia coli, Istituto Superiore di Sanità, 00161 Rome, Italy.
Gianluigi ArdissinoCenter for HUS Control, Prevention and Management, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.
Timo VaaraNorthern Antibiotics Ltd, 00140 Helsinki, Finland.
Martti VaaraNorthern Antibiotics Ltd, 00140 Helsinki, Finland.
Maurizio BrigottiDepartment of Medical and Surgical Sciences (DIMEC), University of Bologna, 40126 Bologna, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hemolytic uremic syndrome (HUS), the main cause of acute renal failure in early childhood, is associated with infections by

Indexed as

Biological sciencesMedical MicrobiologyMicrobiologyNatural sciencesPharmacology

Identifiers

PMID40740497
PMCPMC12309968

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.