Evidence map›Paper›PMID 40740416›Full record

ArticleGynecologic oncology reports2025

Assessing delays in accessing and completing radiotherapy for cervical cancer treatment: A multicenter survey of oncology providers in go further-funded countries in Sub-Saharan Africa.

Caroline G Kernell, Megan Kassick, Jessica M George, Chidinma P Anakwenze, Edward L Trimble, Surbhi Grover

Abstract read
In one paragraph

Article in Gynecologic oncology reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Caroline G KernellUT Southwestern Medical School, 5323 Harry Hines Blvd, Dallas, TX 75390, United States of America.
Megan KassickUniversity of Pennsylvania, Department of Radiation Oncology, Perelman Center for Advanced Medicine, 3400 Civic Center Blvd, Philadelphia, PA 19104, United States of America.
Jessica M GeorgeDepartment of Population and Public Health Sciences Keck School of Medicine, University of Southern California, 2001 N Soto St, Los Angeles, CA 90032, United States of America.
Chidinma P AnakwenzeMD Anderson Cancer Center, Department of Radiation Oncology, 1515 Holcombe Blvd, Houston, TX 77030, United States of America.
Edward L TrimbleNational Institutes of Health, National Cancer Institute, 9609 Medical Center Drive, Bethesda, MD 20892, United States of America.
Surbhi GroverUniversity of Pennsylvania, Department of Radiation Oncology, Perelman Center for Advanced Medicine, 3400 Civic Center Blvd, Philadelphia, PA 19104, United States of America.

Funding

Prognostic value of quantitative HPV viral load in determining cervical cancer treatment response and recurrenceK08CA230170 · NCI · UNIVERSITY OF PENNSYLVANIA · PI GROVER, SURBHI · 2019 to 2023
$1.4M
NCI NIH HHS K08 CA230170
6 · The paper itself

Abstract

Objective: Cervical cancer is a leading cause of cancer death in Sub-Saharan Africa. Go Further provides funds for prevention and screening in Sub-Saharan Africa, but access to treatment for invasive disease remains limited. This survey aims to assess delays in accessing curative-intent chemoradiotherapy for cervical cancer in countries receiving Go Further funding. Methods: Oncology providers in countries receiving Go Further funding (Botswana, Eswatini, Ethiopia, Kenya, Lesotho, Malawi, Mozambique, Namibia, Tanzania, Uganda, Zambia, Zimbabwe) and South Africa were invited to participate in a web-based survey beginning September 2023. Results: Fifteen oncology providers responded, with all countries except Malawi represented. Nearly half (46.3 %) reported wait time of ≥two months for chemoradiotherapy consultation. 93.3 %, 71.4 %, 53.7 % and 73.3 % had access to at least one CT, linear accelerator, cobalt, and brachytherapy machine, respectively. Majority (60 %) reported wait time of <one month to initiate chemoradiotherapy after staging. However, 28.6 % reported >95 % of patients complete external radiotherapy within 42 days, and 33 % reported >95 % of these patients receive brachytherapy. Only 26.7 % reported overall treatment time within 56 days for >95 % of patients. Lack of transportation, funding, and patient fear, were other treatment barriers reported. Conclusion: These results highlight the need for additional chemoradiotherapy resources in Go Further-funded countries. In addition to expanding radiotherapy, supplemental avenues to improve access in Sub-Saharan Africa include addressing barriers that increase wait times along the care continuum and implementing social support. This survey serves as a call to Go Further, highlighting the urgent need for resource allocation for cervical cancer treatment.

Indexed as

Access to healthcareCervical cancerGlobal healthRadiation oncologyRadiotherapySub-Saharan countries

Identifiers

PMID40740416
PMCPMC12309483

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