Wound-Healing Properties of Henna in Pilonidal Sinus Surgery: A Randomized Study.

Background: Wound complications associated with pilonidal sinus (PS) significantly contribute to its high post-operative morbidity. Therefore, speeding up the wound healing process after surgery can help minimize potential complications. This study investigated the effectiveness of Methods: This randomized, double-blind, controlled clinical trial involved 60 patients with open post-operative PS wounds. Participants were randomly divided into three groups: the first group received LIE ointment treatment, the second group used phenytoin as a standard occlusive dressing method and the third group used eucerin ointment as a negative control. In all groups, the wound was cleansed with normal saline and dressed with wet gauze daily. A physician measured the length, depth and volume of the wounds on days 7, 14 and 28 post-PS surgery. Results: After two weeks, the LIE topical ointment significantly decreased the length and depth of the wound compared to phenytoin and eucerin ointments. Additionally, the wound volume in the LIE-treated group was substantially lower than in the other groups ( Conclusion: The study highlighted the wound-healing properties of henna extract. The results indicate that LIE ointment can enhance the wound healing process, thereby lowering the risk of infection and complications in post-operative wounds.