Evidence map›Paper›PMID 40740365›Full record

Observational studyFrontiers in public health2025

Rifampicin-resistant tuberculosis in Fujian Province, Southeast China: a retrospective analysis of drug resistance screening and treatment outcomes, 2019-2024.

Yinfa Zhou, Zhisong Dai, Shufang Lin, Daiquan Chen, Jian Lin, Kun Chen, Yongming Lin, Yanqin Deng

Abstract readObservational Study
In one paragraph

Observational study in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yinfa ZhouFujian Center for Disease Control and Prevention, Fuzhou, China.
Zhisong DaiFujian Center for Disease Control and Prevention, Fuzhou, China.
Shufang LinFujian Center for Disease Control and Prevention, Fuzhou, China.
Daiquan ChenFujian Center for Disease Control and Prevention, Fuzhou, China.
Jian LinFujian Center for Disease Control and Prevention, Fuzhou, China.
Kun ChenFujian Center for Disease Control and Prevention, Fuzhou, China.
Yongming LinFujian Center for Disease Control and Prevention, Fuzhou, China.
Yanqin DengFujian Center for Disease Control and Prevention, Fuzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Backgrounds: Rifampicin-resistant tuberculosis (RR-TB) remains a major challenge to global TB control efforts. In Fujian Province, Southeast China, where RR-TB prevalence has been notably high, understanding epidemiological trends and treatment outcomes is crucial for optimizing interventions. This study aimed to analyze RR-TB characteristics, resistance patterns, and treatment outcomes to inform evidence-based control strategies. Methods: An observational study was conducted utilizing data from China's National Tuberculosis Information Management System, focusing on bacteriologically confirmed tuberculosis cases reported in Fujian Province during 2019-2024. Epidemiological characteristics, drug resistance and outcomes of RR-TB were described as frequency (n) and percentage (%). Risk factors for unsuccessful outcomes were assessed using univariate and multivariate logistic regression. Results: A total of 1,368 RR-TB patients were detected, with an overall resistance rate of 3.7%. The RR rate showed a steady decline year by year ( Conclusion: Fujian Province has demonstrated a steady decline in rifampicin resistance rates, primarily driven by reductions in new TB cases. However, treatment inclusion rate and success rate remains suboptimal, highlighting the need for targeted interventions-including enhanced adherence support, intensive follow-up, and adverse event management-particularly for high-risk groups such as older males and manual laborers. These findings can guide tailored strategies to further reduce RR-TB burden in similar settings.

Indexed as

Antitubercular AgentsRifampinTuberculosis, Multidrug-ResistantAdolescentAdultAgedChinaFemaleHumansMaleMiddle AgedMycobacterium tuberculosisRetrospective StudiesRisk FactorsTreatment OutcomeYoung AdultAntitubercular AgentsRifampinepidemiologyregression analysisrifampicin-resistanttreatment outcometuberculosis

Identifiers

PMID40740365
PMCPMC12307381

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.