ArticleFrontiers in public health2025
Association of skeletal muscle strength and cardiorespiratory fitness with bone mineral density: a cross-sectional study.
Article in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Efficacy and safety of a sustained release ashwagandha root extract capsules on muscle strength and cardiorespiratory endurance in recreationally active individuals: a randomized, double-blind, placebo-controlled trial.Frontiers in nutrition · 2026Trial
- Myokine-mediated mechanisms of immune checkpoint inhibitors-associated colorectal injury and repair in rectal cancer.Frontiers in immunology · 2026Review
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Authors and funding
10 authors.
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Abstract
Background: The high prevalence and increasing severity of osteoporosis have elevated it to a significant global public-health concern, imposing a substantial economic burden. Skeletal muscle strength and cardiorespiratory endurance serve as pivotal metrics in evaluating physical health. They play a vital role in mitigating the risks associated with bone density decline and the development of osteoporosis. This cross-sectional study was carried out among Chinese adults aged 30-60 years. Its aim is to investigate the associations between skeletal muscle strength, cardiorespiratory endurance, and bone density, thereby providing scientific evidence for formulating prevention and intervention strategies against osteoporosis. Method: A handgrip dynamometer was employed to measure the subjects' grip strength, which served as an indicator for assessing their upper-limb muscle strength. Additionally, an isokinetic muscle-strength tester was utilized to determine the subjects' lower-limb isokinetic muscle strength, thereby evaluating the strength of their lower-limb muscles. The exercise cardiopulmonary testing system was utilized to directly measure the subjects' maximum oxygen uptake (VO₂ max) via a treadmill test. This crucial indicator was then employed to assess the subjects' cardiorespiratory fitness (CRF). Moreover, the QCT bone density analysis system was used to measure the thoracolumbar bone density of the subjects, and their bone density levels were evaluated based on the Results: In the final fully adjusted model, a significant positive correlation was detected between grip strength and the BMD T score ( Conclusion: In the 30-60 age group, a significant positive correlation was detected between skeletal muscle strength and bone density. Specifically, in women, lower limb muscle strength was more closely associated with bone density; however, this relationship was not significant in men. Moreover, the association between cardiorespiratory endurance and bone density varied by gender. It was not significant in women but demonstrated a significant positive correlation in the male group.
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