Evidence map›Paper›PMID 40740308›Full record

ReviewVeterinary and animal science2025

Quercetin as a bioactive feed additive: nutritional, antioxidant, and gut health implications in poultry and rabbits.

Ayman Abd El-Aziz, Mahmoud Abo Ghanima, Mahmoud Kamal, Ahmed K Aldhalmi, Mohammad M H Khan, Mohamed E Abd El-Hack

Abstract readReview
In one paragraph

Review in Veterinary and animal science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Potential Host-Directed Mechanisms ofVeterinary sciences · 2026
    Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ayman Abd El-AzizDepartment of Animal Wealth Development, Faculty of Veterinary Medicine, Damanhour University, Damanhour 22511, Egypt.
Mahmoud Abo GhanimaDepartment of Animal Wealth Development, Faculty of Veterinary Medicine, Damanhour University, Damanhour 22511, Egypt.
Mahmoud KamalAnimal Production Research Institute, Agricultural Research Center, Dokki, Giza 12618, Egypt.
Ahmed K AldhalmiCollege of Pharmacy, Al-Mustaqbal University, 51001 Babylon, Iraq.
Mohammad M H KhanDepartment of Biochemistry and Chemistry, Faculty of Biotechnology and Genetic Engineering, Sylhet Agricultural University, 3100 Sylhet, Bangladesh.
Mohamed E Abd El-HackDepartment of Industrial Pharmacy, College of Pharmaceutical Sciences and Drug Manufacturing, Misr University for Science and Technology (MUST), P.O. Box 77, Giza, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Quercetin is a bioactive flavonoid widely distributed in vegetables, grains, and fruits, known for its powerful anti-inflammatory, immunomodulatory, and antioxidant properties. Recently, it has attracted increasing attention as a sustainable and functional additive in animal nutrition. This review explores the existing understanding of the use of quercetin in poultry and rabbit diets, focusing on its impact on growth efficiency, intestinal health, antioxidant, immune function, and the quality of animal-derived foods. In rabbits, dietary supplementation with quercetin (25-100 mg/kg diet) has been associated with enhanced feed efficacy, meat composition, and gut microbial balance. In poultry, including broilers and laying hens, quercetin (up to 200 mg/kg) enhances growth under normal and heat stress conditions, improves meat and egg quality, and modulates oxidative stress markers and gut microbiota. These effects are connected to how quercetin helps control the activity of genes that deal with inflammation, antioxidant enzymes, and the immune system in the gut. Importantly, the review emphasizes the potential of quercetin to improve the nutritional and functional quality of meat and eggs, making it highly relevant for human health and food sustainability. Further studies are encouraged to define optimal dosages and explore synergistic effects with other natural additives. This review offers critical insights into how dietary quercetin can be utilized to support animal health, efficiency, and food product quality, aligning with the global shift toward natural, residue-free feed strategies.

Indexed as

Functional feed additiveGut microbiotaPoultryQuercetinRabbits

Identifiers

PMID40740308
PMCPMC12308014

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.