Evidence map›Paper›PMID 40740264›Full record

ArticleFrontiers in psychiatry2025

Promoting healthy aging through intergenerational exchange and digital empowerment: a pilot randomized controlled trial.

Giulia Cossu, Stefano Lorrai, Alessia Galetti, Alessandra Perra, Massimo Tusconi, Giuseppe Carrà, Antonio Preti, Anita Holzinger, Mauro Giovanni Carta

Registry-linked trialAbstract read
In one paragraph

Article in Frontiers in psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06162871 (The Effect of Social Participation As a Key Determinant of Healthy Aging), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06162871 naactive not recruitingnot on this map

The Effect of Social Participation As a Key Determinant of Healthy Aging

TypeinterventionalSponsorUniversity of CagliariRan2023 to 2025Enrolled20ConditionsHealthy AgingArmsPresentations and interactive debate sessions, with intergenerational exchange
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Giulia CossuDepartment of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy.
Stefano LorraiDepartment of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy.
Alessia GalettiDepartment of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy.
Alessandra PerraDepartment of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy.
Massimo TusconiUniversity Hospital of Cagliari, Cagliari, Italy.
Giuseppe CarràSchool of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy.
Antonio PretiDepartment of Neuroscience, University of Turin, Turin, Italy.
Anita HolzingerTeaching Center, Medical University of Vienna, Wien, Austria.
Mauro Giovanni CartaDepartment of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Social isolation and loneliness are major public health concern among individuals aged 65 and older, as they are associated with increased risks of morbidity and mortality. Intergenerational programs have emerged as promising interventions to mitigate these issues by fostering social participation and enhancing overall well-being. Interventions that also incorporate digital literacy support may further help address the relevant digital divide, which significantly contributes to social exclusion, particularly among older adults. This pilot study aimed to assess the feasibility and preliminary efficacy of a psychosocial intervention focused on intergenerational exchange and digital literacy. Methods: A 12-week crossover randomized controlled trial (RCT) design was employed. The intervention engaged younger and older participants in co-preparing seminar presentations, discussing these, and participating in plenary meetings-both in-person and online-on self-selected health, cultural, and topics meaningful from an individual perspective. Feasibility indicators included dropout rates and participant satisfaction. Preliminary measures of improvement were assessed using the Short Form Health Survey (SF-12) for quality of life, the Brief Social Rhythms Scale (BSRS) for the regularity of social and biological rhythms, and the Patient Health Questionnaire-9 (PHQ-9) for depressive symptoms. Results: A total of 12 participants were included in the experimental group and 9 in the control group. Feasibility outcomes showed an overall dropout rate of 28.57%, similarly to comparable trials. Notably, the attrition rate was lower in the experimental group (16.67%). Participant satisfaction was particularly high (M = 37.06, SD = 3.08). Preliminary analyses revealed a statistically significant improvement only in BSRS; 66.6% vs. 26.67%, Conclusions: The findings suggest very high satisfaction and moderate engagement among older adults involved in the program. Given the positive impact on the regularity of biological and behavioral rhythms-recognized as key protective factors in healthy aging-the improvement observed is particularly promising. Future studies with larger samples and extended follow-up periods are needed to corroborate this preliminary evidence. Clinical trial registration: ClinicalTrials.gov, identifier NCT06162871.

Indexed as

digital literacyintergenerational programsolder adultssocial and biological rhythmssocial isolation

Identifiers

PMID40740264
PMCPMC12308239

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.