Evidence map›Paper›PMID 40740240›Full record

ArticleJournal of Cancer2025

Comprehensive Mendelian randomization and colocalization analysis of plasma proteomics to identify new therapeutic targets for bladder cancer.

Jieming Zuo, Junhao Chen, Zhiyong Tan, Lingxiang Wen, Junxian Zhao, Yuanzhi Fu, Haifeng Wang, Shi Fu, Jiansong Wang

Abstract read
In one paragraph

Article in Journal of Cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jieming ZuoYunnan Institute of Urology, The Second Affiliated Hospital of Kunming Medical University, Kunming 650101, China.
Junhao ChenYunnan Institute of Urology, The Second Affiliated Hospital of Kunming Medical University, Kunming 650101, China.
Zhiyong TanYunnan Institute of Urology, The Second Affiliated Hospital of Kunming Medical University, Kunming 650101, China.
Lingxiang WenKunming Medical University, Kunming City, Yunnan Province, China.
Junxian ZhaoDepartment of Urology, 920th Hospital of Joint Logistics Support Force of Chinese People's Liberation Army, Kunming, Yunnan Province, China.
Yuanzhi FuKunming University of Science and Technology, Kunming City, Yunnan Province, China.
Haifeng WangYunnan Institute of Urology, The Second Affiliated Hospital of Kunming Medical University, Kunming 650101, China.
Shi FuYunnan Institute of Urology, The Second Affiliated Hospital of Kunming Medical University, Kunming 650101, China.
Jiansong WangYunnan Institute of Urology, The Second Affiliated Hospital of Kunming Medical University, Kunming 650101, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bladder cancer is characterized by a high recurrence rate and aggressive behavior, with frequent emergence of chemoresistance. Current treatments such as surgery, chemotherapy, and immunotherapy have limited efficacy, underscoring the urgent need for effective early diagnostic biomarkers and novel targeted therapies.

Indexed as

Bladder cancercirculating proteinsdrug target.proteomics

Identifiers

PMID40740240
PMCPMC12305583

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.