Evidence map›Paper›PMID 40740233›Full record

ArticleJournal of Cancer2025

RBM10 inhibits pancreatic cancer development by suppressing immune escape through PD-1 expression.

Xia Gao, Xiuqin Zhang, Junjie Huang, Zhenyu Tan, Jing Yang, Liuhong Yuan, Pengjun Wang, Feier Chen, Huiyan Wu, Changyi Feng and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of Cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Xia GaoDepartment of Pathology, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Xiuqin ZhangDepartment of Pathology, Tongji Hospital, Tongji University School of Medicine, Shanghai, China.
Junjie HuangDepartment of Pathology, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Zhenyu TanDepartment of Pathology, Tongji Hospital, Tongji University School of Medicine, Shanghai, China.
Jing YangDepartment of Pathology, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Liuhong YuanDepartment of Pathology, Tongji Hospital, Tongji University School of Medicine, Shanghai, China.
Pengjun WangDepartment of Pathology, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Feier ChenDepartment of Pathology, Tongji Hospital, Tongji University School of Medicine, Shanghai, China.
Huiyan WuDepartment of Pathology, Tongji Hospital, Tongji University School of Medicine, Shanghai, China.
Changyi FengDepartment of Pathology, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Hong YuDepartment of Pathology, The Affiliated Taizhou Peoples Hospital of Nanjing Medical University, Taizhou 225300, Jiangsu, China.
Shisan BaoDepartment of Pathology, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Da FuDepartment of Pathology, Tongji Hospital, Tongji University School of Medicine, Shanghai, China.
Kun TaoDepartment of Pathology, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

RNA-binding motif protein-10 (RBM10) plays a role in pancreatic adenocarcinoma (PAAD), though its precise underlying mechanism remains unclear. The current study investigates the role of RBM10 in pancreatic cancer progression and immune regulation. RBM10 expression in pancreatic tissues from PAAD patient was assessed using Western blotting, RT-qPCR, and immunohistochemistry, revealing lower levels in pancreatic cancerous tissues compared to adjacent non-cancerous tissues. This finding aligns with

Indexed as

JAK-STATNK cell.PAADPD-1RBM10

Identifiers

PMID40740233
PMCPMC12305579

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.