ArticleActa Cardiologica Sinica2025
Continuous, In Situ Targeted, Ultrahigh-Concentration Antibiotics for Infections from Cardiac Implantable Electronic Devices: The First Taiwan Case Series.
Article in Acta Cardiologica Sinica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
According to current scientific consensus, the definitive treatment for cardiac implantable electronic device (CIED)-related infection is complete removal of the device with adjunctive antibiotic therapy. However, this approach carries the risk of major complications and mortality during or after lead extraction. Conservative treatment with continuous, in situ targeted, ultrahigh-concentration antibiotics (CITAs) to treat localized CIED infection has been shown to have a high success rate without major complications in high-risk patients. Herein, we describe the details of CITA treatment and our experience with four patients, three of whom successfully avoided the need for lead extraction. CITAs represent a promising alternative approach to lead extraction in patients with localized CIED infections. However, further prospective studies are necessary to definitively establish its effectiveness and potentially modify current consensus recommendations.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.