ReviewNanomedicine (London, England)2025
Bioengineered nanoparticles for targeted topical delivery in wound healing: advances and future outlook.
Review in Nanomedicine (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed.
- Wound Healing Potential of Multifunctional Nanomaterials: Mechanism, Future Prospects, and Challenges.Pharmaceutics · 2026Review
- Therapeutic strategies to enhance proliferation in diabetic wound contraction: a comprehensive review from 1991-2025.Acta diabetologica · 2026Review
- Biofilm-Responsive Nanoplatforms for Infected Wound Reconstruction.International journal of nanomedicine · 2026Review
- The Potential of α-Mangostin-Loaded Chitosan/Collagen Nanoparticles in Hydrogel Formulation for Enhanced Wound Healing.Nanotechnology, science and applications · 2026Article
- Quercetin in skin burn healing: mechanisms, advanced delivery systems, and translational perspectives.Frontiers in bioengineering and biotechnology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The convergence of nanoscale engineering and biomimetics is revolutionizing wound care by enabling the development of bioengineered nanoparticles with exceptional therapeutic precision. This review synthesizes recent advances in nanoparticle-based interventions that mimic biological systems for targeted, controlled, and stage-specific wound healing. Innovations covered include receptor-specific ligand conjugation, bioactive scaffolds, nucleic acid-based systems, microenvironment-responsive nanomaterials, stimuli-activated metal nanoparticles, biosensing platforms, and exosome-mimicking systems. These approaches offer enhanced modulation of the wound microenvironment and promote tissue regeneration, addressing major drawbacks of conventional therapies. Therapeutic efficacy is critically evaluated using data from recent in vitro and in vivo studies. A structured literature search was conducted using PubMed, Scopus, Web of Science, and ScienceDirect, covering publications from January 2015 to June 2025. Relevant studies were selected based on their focus on nanoparticle-based wound-healing strategies, bioengineering innovations, and translational potential. The review also discusses challenges such as biocompatibility, biodistribution, manufacturing scalability, and regulatory hurdles that limit clinical adoption. Finally, this review explores the future paradigm of personalized nanotherapeutics, tailored to individual patient pathophysiology. By summarizing current developments and forecasting future directions, this review highlights the transformative role of bioengineered nanoparticles in next-generation wound healing and regenerative medicine.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.