ArticleSmall (Weinheim an der Bergstrasse, Germany)2025
A Novel Deep Reinforcement Learning Approach for Dynamic Proportional-Integral Control in Scanning Probe Microscopy.
Article in Small (Weinheim an der Bergstrasse, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Artificial Intelligence for Discovery in Life Sciences.Bioconjugate chemistry · 2026Review
- Synthetic data-driven deep learning for label-free autonomous atomic force microscopy.Nature communications · 2026Article
- A Novel Deep Reinforcement Learning Approach for Dynamic Proportional-Integral Control in Scanning Probe Microscopy.Small (Weinheim an der Bergstrasse, Germany) · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Scanning Probe Microscopy (SPM) measurements often encounter challenges due to the nonlinear and time-varying behavior of materials, as well as abrupt changes in structure, properties, or topography. These issues can lead to system instability and imaging artifacts. Traditional proportional-integral (P-I) controllers with fixed parameters struggle to adapt to such conditions. To address this limitation, this study introduces the Parallel Integrated Control and Training System (PICTS), which leverages deep reinforcement learning (DRL) to dynamically adjust control strategies in real time. This approach stabilizes probe-sample interactions, even for samples with sharp edges, soft multiphase materials, or complex topographies. Experimental results demonstrate that the DRL-based controller reduces deflection errors by 26% - 90% compared to commercial fixed-parameter controllers, producing more stable images with fewer artifacts. Statistical analyses confirm improved precision, with error values concentrated near zero. Additionally, the system employs a field-programmable gate array (FPGA) for critical tasks, ensuring efficient operation without the need for high-performance computing. By integrating advanced machine learning, this work enhances imaging quality and stability in demanding environments, paving the way for further innovations in SPM.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.