Evidence map›Paper›PMID 40739742›Full record

ArticleVeterinary ophthalmology2026

Prevalence and Characteristics of Feline Ulcerative Keratitis and Corneal Sequestra in a Referral Population and Comparison Between Brachycephalic and Nonbrachycephalic Cats.

M Frejlich, G Payen

Abstract readComparative Study
In one paragraph

Article in Veterinary ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

M FrejlichDepartment of Ophthalmology, Centre Hospitalier Vétérinaire Frégis, IVC Evidensia France, Gentilly, France.ORCID https://orcid.org/0009-0004-5039-6637
G PayenDepartment of Ophthalmology, Centre Hospitalier Vétérinaire Frégis, IVC Evidensia France, Gentilly, France.

Funding

IVC Evidensia Research Fund
6 · The paper itself

Abstract

objectivesTo investigate the prevalence and characteristics of feline ulcerative keratitis (UK) and corneal sequestra (CS) in brachycephalic and nonbrachycephalic breeds. ANIMALS STUDIED: Brachycephalic and nonbrachycephalic cats. PROCEDURES: Cats diagnosed with UK or CS (Total, 392; UK, 290; CS, 102), between 2013 and 2022, were included. Collected data included signalment, affected eye, lesion characteristics, predisposing factors, and treatment type. UK was classified as superficial (grade 1), stromal (grade 2), or descemetoceles and perforations (grade 3). Sequestra received grade CS or CS

resultsPrevalence of UK was 15% (218/1418) in nonbrachycephalics and 36% (72/202) in brachycephalics (p < .001). No significant differences were noted in the prevalence of grades 2 and 3 between brachycephalics and nonbrachycephalics. Brachycephalics were more affected by central/paracentral corneal ulcers (p = .001) or sequestra (p < .001). Corneal vascularization was more frequent in nonbrachycephalics in both UK (non-BC, 67%; BC: 57%) and CS (non-BC, 74%; BC; 52%) groups. Keratoplasty was more frequently conducted in brachycephalics (p < .001). Overall, 38/286 nonbrachycephalic eyes and 3/128 brachycephalic eyes with UK or CS underwent entropion surgery (p = .002).

conclusionBrachycephalic cats were more affected by UK and CS. Stromal and perforated corneal ulcers were not more frequent in brachycephalics, but corneal lesions were centrally located and less frequently associated with corneal vascularization than in nonbrachycephalics. An inferotemporal entropion was more often associated with UK or CS in nonbrachycephalics.

Indexed as

Cat DiseasesCorneal DiseasesCorneal UlcerCraniosynostosesAnimalsCatsFemaleMalePrevalencecatcorneal ulcerkeratoplastysequestrum

Identifiers

PMID40739742
PMCPMC12951262

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.