Evidence map›Paper›PMID 40739626›Full record

ArticleBMC surgery2025

The impact of flap dehiscence on the long-term speech outcome of furlow palatoplasty.

Yixuan Huang, Bing Shi, Qian Zheng, Jingtao Li

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Article in BMC surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Yixuan HuangState Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Department of Oral&Maxillofacial Surgery, West China Hospital of Stomatology, Sichuan University, No.14 Ren Min Nan Road, Chengdu, Sichuan, 610041, China.ORCID http://orcid.org/0000-0002-7542-9050
Bing ShiState Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Department of Oral&Maxillofacial Surgery, West China Hospital of Stomatology, Sichuan University, No.14 Ren Min Nan Road, Chengdu, Sichuan, 610041, China.
Qian ZhengState Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Department of Oral&Maxillofacial Surgery, West China Hospital of Stomatology, Sichuan University, No.14 Ren Min Nan Road, Chengdu, Sichuan, 610041, China. zq652@163.com.
Jingtao LiState Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Department of Oral&Maxillofacial Surgery, West China Hospital of Stomatology, Sichuan University, No.14 Ren Min Nan Road, Chengdu, Sichuan, 610041, China. lijingtao86@163.com.

Funding

Align Technology Research Program No. AQKY22-2-6Sichuan Science and Technology Program 2022YFS0117
6 · The paper itself

Abstract

backgroundFlap dehiscence is a common complication observed after Furlow palatoplasty, but its impact on speech outcome is unclear. This study aimed to test the hypothesis that flap dehiscence following Furlow palatoplasty significantly increases the risk of adverse long-term speech outcomes.

methodsThis retrospective cohort study reviewed patients with soft cleft palate (SCP), submucous cleft palate (SMCP), or secondary velopharyngeal incompetence (VPI) who underwent Furlow palatoplasty from 2013 to 2023 at a tertiary hospital-based cleft center. The exposure variable was wound healing status, categorized as primary healing (without flap dehiscence), secondary healing (with flap dehiscence), or persistent fistulae formation. The location, size, and healing duration of flap dehiscence were also documented. The primary outcome was postoperative velopharyngeal function, assessed through standardized speech evaluations. Associations were analyzed using univariate and multivariate logistic regression models.

resultsA total of 431 patients receiving Furlow palatoplasty were enrolled, with 12.5% reported flap dehiscence and 3.0% with persistent oronasal fistulae. For both primary cleft repair and secondary VPI correction, the occurrence of flap dehiscence and age at operation were identified as in significant correlation with postoperative velopharyngeal function. Patients with secondary healing demonstrated a higher rate of hypernasality and worse speech intelligibility. In addition, those with dehiscence size larger than 1cm

conclusionFlap dehiscence is a significant prognostic factor in long-term speech outcomes following Furlow palatoplasty. Wound healing monitor is necessary for the comprehensive evaluation of cleft repair techniques.

Indexed as

Cleft PalatePalate, SoftPlastic Surgery ProceduresPostoperative ComplicationsSpeechSurgical FlapsSurgical Wound DehiscenceVelopharyngeal InsufficiencyChildChild, PreschoolFemaleHumansInfantMaleRetrospective StudiesTreatment OutcomeCleft palateFlap dehiscenceFurlow palatoplastyVelopharyngeal incompetenceWound healing

Identifiers

PMID40739626
PMCPMC12309130

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.