Evidence map›Paper›PMID 40739539›Full record

Trial reportBMC anesthesiology2025

A prospective randomized clinical trial on the differential effect of left versus right stellate ganglion block on perioperative stress response.

Wei Jiang, Liu Yang, Xia Zheng

Abstract readRandomized Controlled TrialComparative Study
In one paragraph

Trial report in BMC anesthesiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Wei JiangDeparment of Anesthesiology, Yongchuan Hospital of Chongqing Medical University, No. 439, Xuanhua Road, Yongchuan District, Chongqing, 402106, China.
Liu YangDeparment of Anesthesiology, Yongchuan Hospital of Chongqing Medical University, No. 439, Xuanhua Road, Yongchuan District, Chongqing, 402106, China.
Xia ZhengDeparment of Anesthesiology, Yongchuan Hospital of Chongqing Medical University, No. 439, Xuanhua Road, Yongchuan District, Chongqing, 402106, China. YYHHJJ5555@163.com.

Funding

Research grants in Yongchuan Hospital of Chongqing Medical University, China YJLC201918
6 · The paper itself

Abstract

objectiveThe purpose of this study is to investigate the differential effects of left versus right stellate ganglion block (SGB) on perioperative stress response.

methodsSixty patients scheduled for elective laparoscopic cholecystectomy were randomly divided into two groups, the left SGB (LSGB) group and the right SGB (RSGB) group. After routine general anesthesia, ultrasound-guided left or right SGB was performed 20 min before anesthesia induction in the LSGB and RSGB groups. The primary outcome was the difference in blood pressure and heart rate recorded at T1 (admission), T2 (before anesthesia induction), T3 (immediately after intubation), T4 (after pneumoperitoneum establishment), T5 (postoperative end), and T6 (exit). Serum cortisol levels measured at T1, T3, T4, and T6, and adverse reactions were regarded as secondary outcomes.

resultsThe heart rate at T2 and T3 in the RSGB group was sharply lower than that in the LSGB group (P < 0.05). No significant differences were observed in heart rate and blood pressure in the two groups at the other time points (P > 0.05). No significant differences were observed in serum cortisol levels and adverse reactions between the two groups (P > 0.05).

conclusionRight SGB has a more significant short-term effect on heart rate reduction than left stellate ganglion block. Serum cortisol levels and adverse reactions were comparable between the two groups. CLINICAL TRIAL: The project was registered in the Chinese Clinical Trial Registry (ChiCTR2100053789) on 2021/11/29.

Indexed as

Autonomic Nerve BlockStellate GanglionStress, PhysiologicalAdultBlood PressureCholecystectomy, LaparoscopicFemaleHeart RateHumansHydrocortisoneMaleMiddle AgedProspective StudiesUltrasonography, InterventionalHydrocortisoneNerve blockStellate ganglionStress response

Identifiers

PMID40739539
PMCPMC12312597

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.