Evidence map›Paper›PMID 40739503›Full record

ArticleBMC musculoskeletal disorders2025

Impact of graded compression stockings on deep vein thrombosis incidence after fast-track total knee arthroplasty: a retrospective cohort study.

Dengxian Wu, Kai Fu, Gongan Jiang, Liang Qiao, Yao Yao, Dongyang Chen, Qing Jiang

Abstract read
In one paragraph

Article in BMC musculoskeletal disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Dengxian Wu *Division of Sports Medicine and Adult Reconstructive Surgery, Department of Orthopedic Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, 321 Zhongshan Road, Nanjing, Jiangsu, 210008, PR China.
Kai Fu *Department of Orthopaedics, BenQ Medical Center, The Affiliated BenQ Hospital of Nanjing Medical University, Nanjing, Jiangsu Province, China.
Gongan JiangDivision of Sports Medicine and Adult Reconstructive Surgery, Department of Orthopedic Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, 321 Zhongshan Road, Nanjing, Jiangsu, 210008, PR China.
Liang QiaoDivision of Sports Medicine and Adult Reconstructive Surgery, Department of Orthopedic Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, 321 Zhongshan Road, Nanjing, Jiangsu, 210008, PR China.
Yao YaoDivision of Sports Medicine and Adult Reconstructive Surgery, Department of Orthopedic Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, 321 Zhongshan Road, Nanjing, Jiangsu, 210008, PR China.
Dongyang ChenDivision of Sports Medicine and Adult Reconstructive Surgery, Department of Orthopedic Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, 321 Zhongshan Road, Nanjing, Jiangsu, 210008, PR China. 28617621@qq.com.
Qing JiangDivision of Sports Medicine and Adult Reconstructive Surgery, Department of Orthopedic Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, 321 Zhongshan Road, Nanjing, Jiangsu, 210008, PR China. qingj@nju.edu.cn.

Funding

Jiangsu Province Medical Innovation Center of Orthopedic Surgery CXZX202214Jiangsu Provincial Key Medical Center Foundation, Jiangsu Provincial Medical Outstanding Talent Foundation, Jiangsu Provincial Medical Youth Talent Foundation and Jiangsu Provincial Key Medical Talent Foundation, the Fundamental Research Funds for the Central Universities 14380493, 14380494Major Project of NSFC 81991514National Key Research and Development Project 2021YFA1201404National Major Research plan of NSFC 92368201
6 · The paper itself

Abstract

backgroundVenous thromboembolism (VTE) is a significant complication following total knee arthroplasty (TKA), with considerable implications for patient outcomes. The purpose of this study is to assess the incidence of VTE after fast-track TKA at our center and to evaluate whether the use of graded compression stockings (GCS) can further reduce VTE incidence within this regimen.

methodsA total of 660 patients undergoing primary TKA between January 1, 2018, and December 31, 2022, were included. Patients were categorized into two groups: GCS group (n = 390) and non-GCS group (n = 270). Knee-length GCS were applied to patients in the GCS group. Diagnosis of deep vein thrombosis (DVT) was confirmed by bilateral lower extremity duplex venous ultrasonography. Incidence and locations of thrombosis were recorded. Demographic characteristics, laboratory indices, and surgical variables were collected. Univariate and multivariate regression analyses were performed to identify risk factors for thrombosis.

resultsThe overall incidence of VTE after fast-track TKA was 6.2% (41/660), with no cases of proximal DVT or pulmonary embolism (PE). The incidence of DVT was significantly lower in the GCS group compared to the non-GCS group (3.8% vs. 9.6%). After adjusting for confounders, multivariate analysis demonstrated that absence of GCS, older age, and history of cardiovascular disease were independent risk factors for postoperative DVT.

conclusionIn conclusion, this study found a low incidence of VTE after fast-track TKA, and the use of GCS may further reduce the occurrence of early postoperative calf muscular vein thrombosis (CMVT) when combined with anticoagulants plus intermittent pneumatic compression (IPC).

Indexed as

Arthroplasty, Replacement, KneePostoperative ComplicationsStockings, CompressionVenous ThrombosisAgedFemaleHumansIncidenceMaleMiddle AgedRetrospective StudiesRisk FactorsVenous ThromboembolismDeep vein thrombosis (DVT)Fast-trackGraded compression stockings (GCS)Intermittent pneumatic compression (IPC)Total knee arthroplasty (TKA)

Identifiers

PMID40739503
PMCPMC12309214

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.