Evidence map›Paper›PMID 40739476›Full record

Trial reportBMC anesthesiology2025

Optimizing post-thoracotomy pain management: comparing erector spinae vs. paravertebral block in thoracotomy patients: a prospective randomized study.

Kerem Baser, Ozal Adiyeke, Ergun Mendes, Funda Gumus Ozcan

Registry-linked trialAbstract readRandomized Controlled TrialComparative Study
In one paragraph

Trial report in BMC anesthesiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06964698 (Erector Spinae Plane Block Versus Paravertebral Block for Post-Thoracotomy Pain Syndrome in Thoracotomy Patients; A Prospective Observational Study), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06964698 completednot on this map

Erector Spinae Plane Block Versus Paravertebral Block for Post-Thoracotomy Pain Syndrome in Thoracotomy Patients; A Prospective Observational Study

Typeobservational_patient_registrySponsorBaşakşehir Çam & Sakura City HospitalRan2022 to 2023Enrolled60ConditionsLung Diseases, Lung Cancers
3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kerem BaserHealth Ministery Sancaktepe Sehıt Prof Dr Ilhan Varank Research and Education, Department of Anesthesiology And Reanimation Clinic, Istanbul, Istanbul, Turkey.ORCID http://orcid.org/0000-0003-0289-635X
Ozal AdiyekeDepartment Of Anesthesiology And Reanimation Clinic, Health Ministery Basaksehir Cam And Sakura City Hospital, Basaksehir, Istanbul, Turkey. ozaladiyeke@gmail.com.ORCID http://orcid.org/0000-0001-5725-0981
Ergun MendesDepartment Of Anesthesiology And Reanimation Clinic Zeytinburnu, Koc University Hospital, Istanbul, Turkey.ORCID http://orcid.org/0000-0003-4350-6055
Funda Gumus OzcanDepartment Of Anesthesiology And Reanimation Clinic, Health Ministery Basaksehir Cam And Sakura City Hospital, Basaksehir, Istanbul, Turkey.ORCID http://orcid.org/0000-0003-0641-7977

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPostoperative pain can lead to serious complications in the short and medium term. It may also increase the risk of converting acute pain into chronic pain, leading to the development of postthoracotomy pain syndrome (PTPS). The aim of this study was to demonstrate the effectiveness of erector spinae plane block (ESPB) and paravertebral block (PVB) in managing acute postoperative pain and preventing the development of PTPS in patients undergoing thoracotomy and lobectomy.

methodsThis prospective, randomized study included American Society of Anesthesiologists (ASA) class II-III patients aged 18–70 years who underwent elective unilateral lobectomy via a thoracotomy. The study was conducted at Başakşehir Çam and Sakura City Hospital, following approval from the hospital’s ethics committee on May 20, 2022 (protocol number: KAEK.2022.05.155). Patients were randomly assigned into ESPB (n = 30) and PVB (n = 30) groups using a computer-generated randomization sequence prior to surgery. Intravenous patient-controlled analgesia (PCA) was provided for 24 h postoperatively. Resting numerical rating scala (NRS) and Prince Henry Hospital Pain Scale (PHHPS) scores were evaluated at 0, 2, 6, 12, and 24 h after surgery. Pain levels were further assessed via telephone interviews using the NRS at 2 weeks and 2 months postoperatively.

resultsThe baseline NRS score was significantly lower in the PVB group (3.97 ± 0.61) compared to the ESPB group (4.37 ± 0.85) (p = 0.044). The mean number of PCA requests, mean opioid consumption and number of patients receiving rescue analgesics were significantly lower in the PVB group than in the ESPB group (p < 0.05). No significant differences were observed between the groups in hemodynamic parameters (p > 0.05). PTPS developed in 3 patients (1 in PVB, 2 in ESPB), with no significant intergroup difference (p = 0.561).

conclusionsPVB and ESPB provided effective acute pain control after thoracotomy, with PVB showing superior outcomes in analgesic use and pain scores. Early management of postoperative pain may improve short-term recovery and potentially reduce PTPS incidence, which was 5% in our study—lower than reported in the literature.

trial registrationClinicalTrials.gov (ID NCT06964698). The clinical trial was retrospectively registered on April 02, 2025.

Indexed as

Nerve BlockPain ManagementPostoperative PainThoracotomyAdolescentAdultAgedAnalgesia, Patient-ControlledFemaleHumansMaleMiddle AgedPain MeasurementParaspinal MusclesProspective StudiesYoung AdultErector spinae plane blockParavertebral blockPost-operative pain syndromeThoracotomy

Identifiers

PMID40739476
PMCPMC12308981

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.