Trial reportBMC anesthesiology2025
Effect of nasal mask oxygenation on incidence of hypoxemia during gastroscopy with propofol sedation in patients at risk of hypoxemia: a prospective randomized controlled study.
Trial report in BMC anesthesiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Efficacy of BiPAP/CPAP versus COT in patients with obstructive sleep apnea or obesity undergoing sedated gastroenteroscopy: a meta-analysis.Journal of anesthesia · 2026Pooled it
- Efficacy and safety of nasal mask compared to nasal cannula during procedural sedation in gastroscopy: a systematic review, meta-analysis, and trial sequential analysis.BMC anesthesiology · 2026Pooled it
- An Oxycodone-Based Conscious Analgesia Strategy with Supplemental Low-Dose Propofol Improves Safety in Elderly Obese Patients Undergoing Gastroscopy: A Prospective Randomized Controlled Trial.Drug design, development and therapy · 2026Trial
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHypoxemia is a prevalent complication during sedated gastroscopy and may result in significant adverse outcomes. We aimed to determine if nasal mask oxygenation could decrease the incidence of hypoxemia compared with standard oxygenation in patients with obesity or obstructive sleep apnea (OSA) undergoing gastroscopy under deep sedation.
methodsIn a prospective randomized study, 120 patients aged 18 to 70 years, diagnosed with obesity or OSA, who underwent sedated gastroscopy, were randomized into two groups: Group M (nasal mask oxygenation) or Group C (nasal cannula oxygenation) from June 2024 to January 2025. The primary outcome was the incidence of hypoxemia (75%≤SpO
resultsNasal mask oxygenation decreased the incidence of hypoxemia from 32.8 to 8.5% ( P < 0.001), subclinical respiratory depression from 48.3 to 20.3% ( P < 0.001), and severe hypoxemia from 13.8 to 1.7% ( P < 0.001). No significant differences in other sedation-related adverse events were observed between the two groups.
conclusionIn patients with obesity or OSA, nasal mask oxygenation during gastroscopy with propofol sedation significantly reduced the incidences of hypoxemia, subclinical respiratory depression, and severe hypoxemia without increasing other adverse events.
trial registrationChinese Clinical Trial Registry (ChiCTR2400085162).
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