ArticleSleep & breathing = Schlaf & Atmung2025
Prevalence and characterization of positional obstructive sleep apnea with peripheral arterial tonometry in a real-world Colombian cohort.
Article in Sleep & breathing = Schlaf & Atmung, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Beyond a Single Hypoxic Burden Value: Hypoxic Burden Ratio Assessed by Peripheral Arterial Tonometry in Obstructive Sleep Apnea.Nature and science of sleep · 2026Article
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2 authors.
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Abstract
purposePositional obstructive sleep apnea (POSA) is a common but heterogeneous phenotype of obstructive sleep apnea (OSA), and its identification may inform more personalized therapy. This study aims to characterize POSA and non-POSA phenotypes in a real-world cohort using peripheral arterial tonometry-based home sleep apnea testing (PAT-HSAT).
methodsA retrospective analysis was performed on adults referred for PAT-HSAT at a single center in Colombia. Subjects were classified as POSA or non-POSA based on standard positional indices. Clinical variables, oxygen desaturation index (ODI4%), time with oxygen saturation below 90% (T < 90), and other sleep metrics were compared between groups.
resultsThe prevalence of POSA varied by classification: Cartwright (38.4%), Levendowski (30.8%), Bignold (21.7%), Mador (7.0%), and APOC Global (46.1%). Significant physiological differences were observed between APOC subgroups. APOC I exhibited the lowest respiratory event indices (pAHI 3%: 10.6 events/h; ODI4%: 5.7 events/h), while APOC III patients showed severe respiratory compromise and hypoxaemia (pAHI 3%: 51.0 events/h; ODI4%: 34.9 events/h; T < 90: 166.8 min; all p < 0.001).
conclusionPOSA is prevalent in this Colombian cohort, and the APOC classification effectively captures a broad spectrum of positional phenotypes. Unlike other classification systems, APOC provides a more comprehensive approach to positional characterization. Furthermore, PAT-HSAT emerges as a valid and ecologically alternative tool for postural phenotyping, offering potential for more individualized management of OSA based on positional susceptibility.
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