Evidence map›Paper›PMID 40739418›Full record

ArticleSurgical endoscopy2025

The impact of preoperative optimization for abdominal wall reconstruction on long-term glucose control and smoking cessation.

Alexis M Holland, Alynna J Wiley, Samantha W Kerr, William R Lorenz, Daniel G Zeter, Stephanie M Jensen, Gregory T Scarola, Brittany S Mead, Kent W Kercher, Sullivan A Ayuso and 2 more

Abstract read
PubMed Publisher
In one paragraph

Article in Surgical endoscopy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Beyond the Operating Room: The Lasting Impact of Preoptimization in Abdominal Wall Reconstruction.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Alexis M HollandDivision of Gastrointestinal and Minimally Invasive Surgery, Department of Surgery, Carolinas Medical Center, Charlotte, NC, USA.
Alynna J WileyDivision of Gastrointestinal and Minimally Invasive Surgery, Department of Surgery, Carolinas Medical Center, Charlotte, NC, USA.
Samantha W KerrDivision of Gastrointestinal and Minimally Invasive Surgery, Department of Surgery, Carolinas Medical Center, Charlotte, NC, USA.
William R LorenzDivision of Gastrointestinal and Minimally Invasive Surgery, Department of Surgery, Carolinas Medical Center, Charlotte, NC, USA.
Daniel G ZeterDivision of Gastrointestinal and Minimally Invasive Surgery, Department of Surgery, Carolinas Medical Center, Charlotte, NC, USA.
Stephanie M JensenDivision of Gastrointestinal and Minimally Invasive Surgery, Department of Surgery, Carolinas Medical Center, Charlotte, NC, USA.
Gregory T ScarolaDivision of Gastrointestinal and Minimally Invasive Surgery, Department of Surgery, Carolinas Medical Center, Charlotte, NC, USA.
Brittany S MeadDivision of Minimally Invasive and Bariatric Surgery, Rush University Medical Center, Chicago, IL, USA.
Kent W KercherDivision of Gastrointestinal and Minimally Invasive Surgery, Department of Surgery, Carolinas Medical Center, Charlotte, NC, USA.
Sullivan A AyusoDepartment of Surgery, Endeavor Health, Evanston Hospital, Grainger Center for Simulation, 2650 Ridge Ave, Evanston, IL, 60201, USA.
Vedra A AugensteinDivision of Gastrointestinal and Minimally Invasive Surgery, Department of Surgery, Carolinas Medical Center, Charlotte, NC, USA.
B Todd HenifordDepartment of Surgery, Endeavor Health, Evanston Hospital, Grainger Center for Simulation, 2650 Ridge Ave, Evanston, IL, 60201, USA. todd.heniford@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPoorly controlled diabetes mellitus (DM) and tobacco use are known risk factors for surgical complications, particularly poor wound healing and infection. Thus, preoperative optimization prior to elective abdominal wall reconstruction (AWR) to lower patients' glycated hemoglobin (HbA1c) and achieve smoking cessation improves surgical outcomes and patients' overall health. The impact of surgeons and surgery on long-term maintenance of preoptimization is not adequately described, so this study evaluated the sustainability of preoptimized HbA1c and smoking status after AWR.

methodsA prospectively maintained hernia database was reviewed for diabetic patients with HbA1c > 7.2 and actively smoking patients preoptimized before open AWR. Patients' HbA1c improved ≤ 7.2 and smoking cessation achieved for ≥ 4 weeks preoperatively. HbA1c and smoking status were recorded at initial consultation, surgery, and most recent follow-up. Standard analyses were performed.

resultsOf 51 optimized diabetic patients, HbA1c decreased from 8.5 ± 1.6 to 6.5 ± 0.6 after 10.6 ± 12.9 months of preoptimization (p < 0.001). HbA1c was 6.9 ± 1.5 (p < 0.001) at most recent follow-up, 43.0 ± 36.1 months postoperatively. Postoperatively, 63.2% of optimized patients maintained HbA1c ≤ 7.2; 95.8% of those continued to decrease their HbA1c after surgery. Of non-optimized patients, 22.2% improved their HbA1c ≤ 7.2 postoperatively. Average HbA1c was not different between optimized and non-optimized patients at initial consultation, but optimized patients had significantly lower HbA1c than non-optimized patients at most recent follow-up (6.9 ± 1.5 vs. 8.4 ± 1.7; p < 0.001). Seventy smoking patients at consultation achieved smoking cessation by surgery. With 28.1 ± 34.1 months follow-up, 58.6% continued to abstain from tobacco use. Of non-optimized patients, only 14.9% quit smoking postoperatively.

conclusionsDiabetic and smoking patients were successfully preoptimized before elective AWR. Of patients meeting preoperative requirements for glucose control and smoking cessation, 63.2% maintained HbA1c ≤ 7.2 and 58.6% maintained smoking cessation with long-term follow-up postoperatively. The longevity of preoptimization demonstrates that surgeons can impact patients' long-term health well beyond AWR.

Indexed as

Abdominal WallGlycated HemoglobinGlycemic ControlHernia, VentralHerniorrhaphyPreoperative CareSmoking CessationAdultAgedBlood GlucoseDiabetes MellitusFemaleHumansMaleMiddle AgedRetrospective StudiesBlood GlucoseGlycated HemoglobinAbdominal wall reconstructionDiabetesHerniaPrehabilitationPreoperative optimizationSmoking cessation

Identifiers

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.