Evidence map›Paper›PMID 40739417›Full record

ArticleSurgical endoscopy2025

Venous thromboembolism after ventral hernia repair with transversus abdominis release.

Kimberly P Woo, Sergio Mazzola Poli de Figueiredo, Sarah L Larson, Joseph D Quick, Sara M Maskal, Daphne Remulla, William C Bennett, Kimberly S Miles, Chao Tu, Lucas R Beffa and 5 more

Abstract read
In one paragraph

Article in Surgical endoscopy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Kimberly P WooDepartment of General Surgery, Digestive Disease Institute, Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH, 44195, USA. wook2@ccf.org.ORCID http://orcid.org/0009-0001-4601-1309
Sergio Mazzola Poli de FigueiredoDepartment of General Surgery, Digestive Disease Institute, Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH, 44195, USA.
Sarah L LarsonDepartment of General Surgery, Digestive Disease Institute, Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH, 44195, USA.
Joseph D QuickDepartment of General Surgery, Digestive Disease Institute, Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH, 44195, USA.
Sara M MaskalDepartment of General Surgery, Digestive Disease Institute, Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH, 44195, USA.
Daphne RemullaDepartment of General Surgery, Digestive Disease Institute, Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH, 44195, USA.
William C BennettDepartment of General Surgery, Digestive Disease Institute, Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH, 44195, USA.
Kimberly S MilesDepartment of General Surgery, Digestive Disease Institute, Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH, 44195, USA.
Chao TuDepartment of Quantitative Health Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA.
Lucas R BeffaDepartment of General Surgery, Digestive Disease Institute, Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH, 44195, USA.
Clayton C PetroDepartment of General Surgery, Digestive Disease Institute, Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH, 44195, USA.
Ajita S PrabhuDepartment of General Surgery, Digestive Disease Institute, Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH, 44195, USA.
David M KrpataDepartment of General Surgery, Digestive Disease Institute, Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH, 44195, USA.
Michael J RosenDepartment of General Surgery, Northwestern Medicine, Chicago, IL, USA.
Benjamin T MillerDepartment of General Surgery, Digestive Disease Institute, Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH, 44195, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionVenous thromboembolism (VTE) events, such as pulmonary embolism (PE) and deep venous thrombosis (DVT), are a significant source of morbidity and mortality after major abdominal wall reconstruction. We aim to describe the incidence of VTE events in patients undergoing ventral hernia repair (VHR) with transversus abdominis release (TAR) at our institution.

methodsThe Abdominal Core Health Quality Collaborative registry was queried for patients, 18 years and older, who underwent VHR with TAR at our institution between August 2014 and December 2023. Patient characteristics and operative details were obtained from the registry. Patient electronic medical records were reviewed for outcomes. The primary study outcome was the incidence of VTE, including PE and DVT, within 8 weeks postoperatively. Secondary outcomes included time to VTE, VTE chemoprophylaxis protocol used, VTE management, and complications.

resultsOf the 3555 patients who underwent abdominal wall reconstruction and met inclusion criteria, 100 patients experienced (2.8%) VTE events; 58 patients had a PE and 42 had DVTs. The median time to a VTE event was 7 (IQR 4-14) days after surgery, and 27% of VTE events occurred after hospital discharge. Of the patients who experienced a VTE event, 77 received preoperative chemoprophylaxis and 66 patients received postoperative chemoprophylaxis beginning on the day of surgery. In 19 patients, chemoprophylaxis was interrupted prior to development of VTE. Most patients (n = 88) were managed with systemic anticoagulation, and 18.1% had a bleeding complication related to anticoagulation treatment.

conclusionPatients undergoing major abdominal wall reconstruction are at high risk for venous thromboembolism events, even after hospital discharge. Further studies are needed to determine risk factors associated with VTE in this specific patient population to optimize perioperative anticoagulation strategies.

Indexed as

Hernia, VentralHerniorrhaphyPostoperative ComplicationsVenous ThromboembolismAbdominal MusclesAdultAgedAnticoagulantsFemaleHumansIncidenceMaleMiddle AgedRegistriesRetrospective StudiesAnticoagulantsAbdominal wall reconstructionDeep vein thrombosisPulmonary embolismTransversus abdominis releaseVenous thromboembolismVentral hernia repair

Identifiers

PMID40739417
PMCPMC12500807

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.