Evidence map›Paper›PMID 40739352›Full record

ArticleNature2025

Remodelling of corticostriatal axonal boutons during motor learning.

Mengjun Sheng, Di Lu, Richard H Roth, Fuu-Jiun Hwang, Kaiwen Sheng, Jun B Ding

Abstract read
In one paragraph

Article in Nature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Electromechanically induced membrane restructuring enables learning and memory.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Mengjun Sheng *Department of Neurosurgery, Stanford University School of Medicine, Stanford, CA, USA. mjsheng89@gmail.com.ORCID 0000-0002-1440-3447
Di Lu *Department of Neurosurgery, Stanford University School of Medicine, Stanford, CA, USA.ORCID 0000-0003-1177-5672
Richard H RothDepartment of Neurosurgery, Stanford University School of Medicine, Stanford, CA, USA.ORCID 0000-0002-6855-999X
Fuu-Jiun HwangDepartment of Neurosurgery, Stanford University School of Medicine, Stanford, CA, USA.
Kaiwen ShengDepartment of Neurosurgery, Stanford University School of Medicine, Stanford, CA, USA.
Jun B DingDepartment of Neurosurgery, Stanford University School of Medicine, Stanford, CA, USA. dingjun@stanford.edu.ORCID 0000-0003-0690-1312

Funding

Dopamine modulation of synaptic plasticity and integration in the striatumR01NS091144 · NINDS · STANFORD UNIVERSITY · PI Jun Ding · 2015 to 2026
$4.2M
Role of thalamic modulation in motor learningK99NS130078 · NINDS · STANFORD UNIVERSITY · PI ROTH, RICHARD · 2023 to 2024
$246k
NINDS NIH HHS K99 NS130078NINDS NIH HHS R01 NS091144
6 · The paper itself

Abstract

Motor skill learning induces long-lasting synaptic plasticity at dendritic spines

Indexed as

Corpus StriatumLearningMotor CortexMotor SkillsNeuronal PlasticityPresynaptic TerminalsAnimalsAxonsFemaleMaleMiceMice, Inbred C57BLReward

Identifiers

PMID40739352
PMCPMC12488484

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.