ArticleNature2025
Respiratory viral infections awaken metastatic breast cancer cells in lungs.
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Article in Nature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.
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51citing papers in PubMed
–field-weighted citation impact
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Who cites it
51 citing papers in PubMed.
- SARS-CoV-2 mRNA Vaccination Improved Survival in NSCLC Treated With Radiotherapy.Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer · 2026Article
- Olfactory Tuft Cells Are Critical to Basal Inflammation, Innate Immune Response to Viral Infection, and Modulation of Quiescent Stem Cell Activation, Proliferation and Differentiation.Cell proliferation · 2026Article
- COVID-19 mRNA Vaccines as Antigen-Agnostic Immunomodulators: A Repurposing Perspective.Medical sciences (Basel, Switzerland) · 2026Review
- Impact of the COVID-19 pandemic on cancer incidence, stage, mortality, and short-term survival in Ireland: a population-based analysis.ESMO real world data and digital oncology · 2026Article
- Does acute inflammation triggered by infection promote cancer progression?PLoS biology · 2026Review
- Reprogramming pulmonary B cells by ANXA1 silencing halts lung metastatic niche formation in breast cancer.Journal of nanobiotechnology · 2026Article
- From Nucleobases to Bioactive NHC-Based Gold and Silver Complexes With Anticancer and Antiviral Activity.ChemMedChem · 2026Article
- Overcoming Transmission Barriers: A Dual-Functional Adhesive Hydrogel for Direct Monkeypox Virus Neutralization and Wound Healing.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Article
- A randomized controlled trial protocol of herbal formulas for modifying susceptible body constitution to enhance COVID-19 resistance in Hong Kong residents.Journal of thoracic disease · 2026Article
- The pro-tumorigenic functions of cancer-associated adipocytes are dependent on the mitochondrial chaperone tumor necrosis factor receptor-associated protein 1.Signal transduction and targeted therapy · 2026Article
- Virus infections and cancers: from mechanisms to therapeutics.Molecular biomedicine · 2026Review
- SARS-CoV-2 and Cancer Biology: Exploring the Mechanistic Links.Cancer reports (Hoboken, N.J.) · 2026Review
- "Immune senescence and dormant tumor cells: reconceptualizing breast cancer recurrence as an affliction of aging and chronic inflammation".Annals of medicine and surgery (2012) · 2026Review
- The sleeping threat: targeting cancer dormancy to transform metastasis therapy.Nature reviews. Cancer · 2026Review
- Intrinsic and extrinsic regulators of cancer dormancy and awakening.Journal of the National Cancer Center · 2026Review
- Comprehensive Immunophenotyping of Monocytes and Dendritic Cells Suggests Distinct Pathophysiology in Chronic Fatigue Syndrome and Long COVID.International journal of molecular sciences · 2026Article
- Type I interferons induced upon respiratory viral infection impair lung metastatic initiation.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- The metabolic profiles of cancer stem cells.Stem cell research & therapy · 2026Review
- IL-1-mediated inflammation promotes metastatic dissemination and resistance to EGFR-targeted therapy.NPJ precision oncology · 2026Article
Corrections and comments
- Update of
Authors and funding
29 authors.
Shi B Chia *Department of Biochemistry and Molecular Genetics, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Bryan J Johnson *Department of Biochemistry and Molecular Genetics, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.ORCID 0000-0002-2328-3715
Junxiao HuDepartment of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Felipe Valença-PereiraDepartment of Immunology and Microbiology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.ORCID 0000-0003-2650-5528
Marc Chadeau-HyamDivision of Environmental Epidemiology, Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands.ORCID 0000-0001-8341-5436
Fernando GuntoroMRC Centre for Environment and Health, Imperial College London, London, United Kingdom.
Hugh MontgomeryDepartment of Medicine, University College London, London, United Kingdom.ORCID 0000-0001-8797-5019
Meher P BoorgulaUniversity of Colorado Comprehensive Cancer Center, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Varsha SreekanthUniversity of Colorado Comprehensive Cancer Center, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Andrew GoodspeedUniversity of Colorado Comprehensive Cancer Center, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Bennett DavenportDepartment of Immunology and Microbiology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.ORCID 0000-0001-8155-191X
Marco De DominiciDepartment of Biochemistry and Molecular Genetics, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.ORCID 0000-0002-1019-1715
Vadym ZaberezhnyyDepartment of Biochemistry and Molecular Genetics, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Wolfgang E SchleicherDepartment of Biochemistry and Molecular Genetics, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Dexiang GaoDepartment of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.ORCID 0000-0003-3920-7060
Andreia N CadarUConn Center On Aging, University of Connecticut School of Medicine and UConn Health, Farmington, CT, USA.ORCID 0000-0002-1304-5844
Lucia Petriz-OtañoDepartment of Cell Biology, Cancer Dormancy Institute, Montefiore Einstein Comprehensive Cancer Center, Albert Einstein College of Medicine, Bronx, NY, USA.
Michael PapanicolaouDepartment of Cell Biology, Cancer Dormancy Institute, Montefiore Einstein Comprehensive Cancer Center, Albert Einstein College of Medicine, Bronx, NY, USA.
Afshin BeheshtiCOVID-19 International Research Team, Medford, MA, USA.
Stephen B BaylinCOVID-19 International Research Team, Medford, MA, USA.ORCID 0000-0003-3697-3798
Joseph W GuarnieriCenter for Mitochondrial and Epigenomic Medicine, Division of Human Genetics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Douglas C WallaceCenter for Mitochondrial and Epigenomic Medicine, Division of Human Genetics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.ORCID 0000-0002-7480-8278
James C CostelloUniversity of Colorado Comprehensive Cancer Center, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Jenna M BartleyUConn Center On Aging, University of Connecticut School of Medicine and UConn Health, Farmington, CT, USA.ORCID 0000-0003-0302-975X
Thomas E MorrisonDepartment of Immunology and Microbiology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.ORCID 0000-0002-1811-2938
Roel VermeulenDivision of Environmental Epidemiology, Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands.ORCID 0000-0003-4082-8163
Julio A Aguirre-GhisoDepartment of Cell Biology, Cancer Dormancy Institute, Montefiore Einstein Comprehensive Cancer Center, Albert Einstein College of Medicine, Bronx, NY, USA.ORCID 0000-0002-6694-6507
Mercedes RinconUniversity of Colorado Comprehensive Cancer Center, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.ORCID 0000-0002-6663-2225
James DeGregoriDepartment of Biochemistry and Molecular Genetics, University of Colorado Anschutz Medical Campus, Aurora, CO, USA. james.degregori@cuanschutz.edu.ORCID 0000-0002-1287-1976
Funding
University of Colorado Cancer Center Support Grant - Lung Cancer Patient-Derived Xenografts with Autologous Human Immune SystemsP30CA046934 · NCI · UNIVERSITY OF COLORADO DENVER · PI James V Degregori · 1988 to 2026
$117.0MWORD PROCESSORP30CA013330 · NCI · YESHIVA UNIVERSITY · PI Ulrich Steidl · 1985 to 2026
$111.2MResearch Education ComponentP30AG067988 · NIA · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI Richard H Fortinsky, GEORGE A KUCHEL · 2021 to 2026
$9.5MFunctional Determinants of Metastatic DormancyR01CA109182 · NCI · STATE UNIVERSITY OF NEW YORK AT ALBANY · PI AGUIRRE-GHISO, JULIO A. · 2005 to 2025
$8.3MRole of Adaptive Immunity in Etiology of Alzheimer’s Disease andAlzheimer’s Disease-Related DementiasR01AG078814 · NIA · CHILDREN'S HOSP OF PHILADELPHIA · PI Douglas C Wallace · 2022 to 2026
$4.2MAnti-tumor immunity and intestinal microbiota are modulated by mitochondrial DNAR01CA259635 · NCI · CHILDREN'S HOSP OF PHILADELPHIA · PI Douglas C Wallace · 2022 to 2026
$3.2MPredoctoral Training in the Genetics of Development, Disease and RegenerationT32GM141742 · NIGMS · UNIVERSITY OF COLORADO DENVER · PI Bruce H Appel, Jeffrey Kyle Moore · 2021 to 2026
$1.9MEnhancing mitochondrial metabolism to improve anti-tumor CD8 immune responseR01CA260909 · NCI · UNIVERSITY OF COLORADO DENVER · PI Mercedes Rincon · 2022 to 2026
$1.9MImpact of Senolytics on Aged Vaccine ResponsesR01AI173305 · NIAID · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI Jenna Bartley · 2023 to 2026
$1.7MTAKEOFF: Targeting Aging with Ketone Ester in Older adults for Function in FrailtyR01AG081226 · NIA · BUCK INSTITUTE FOR RESEARCH ON AGING · PI BARTLEY, JENNA, NEWMAN, JOHN C · 2023 to 2024
$1.5MRole of respiratory viral infections and inflammation in promoting metastatic outgrowth in the lungR01CA301643 · NCI · UNIVERSITY OF COLORADO DENVER · PI Julio A. Aguirre-Ghiso, James V Degregori · 2025 to 2026
$1.3MRegenerative Engineering of Musculoskeletal Tissues- a Convergence Doctoral Training ProgramT32AR079114 · NIAMS · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI LAURENCIN, CATO T. · 2021 to 2025
$1.1MBLRD VA I01 BX004495NCI NIH HHS P30 CA013330NCI NIH HHS P30 CA046934NCI NIH HHS R01 CA109182NCI NIH HHS R01 CA259635NCI NIH HHS R01 CA260909NCI NIH HHS R01 CA301643NIAID NIH HHS R01 AI173305NIAMS NIH HHS T32 AR079114NIA NIH HHS P30 AG067988NIA NIH HHS R01 AG078814NIA NIH HHS R01 AG081226NIGMS NIH HHS T32 GM141742
Abstract
Breast cancer is the second most common cancer globally, with most deaths caused by metastatic disease, often following long periods of clinical dormancy
Indexed as
Breast NeoplasmsCOVID-19LungLung NeoplasmsOrthomyxoviridae InfectionsAnimalsCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesCell ProliferationFemaleHumansInterleukin-6Lymphocyte ActivationMiceNeoplasm MetastasisSARS-CoV-2Interleukin-6
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.