Evidence map›Paper›PMID 40739233›Full record

SynthesisJournal of cardiothoracic surgery2025

Knowledge domains and hotspots in corticosteroid use for cardiac surgery: a 23-Year bibliometric and visualized analysis.

Wan-Wan Zou, Qi-Kun Zhu, Song Yang, En-Ze Bian, Wei-Zhong Zhuang, Jian-Zheng Cen, Qiang Gao

Abstract readMeta-Analysis
In one paragraph

Synthesis in Journal of cardiothoracic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Wan-Wan Zou *School of Medicine, South China University of Technology, Guangzhou, 510006, China.
Qi-Kun Zhu *Department of Cardiovascular Surgery, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, Guangzhou, 510080, China.
Song YangDepartment of Cardiovascular Surgery, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, Guangzhou, 510080, China.
En-Ze BianDepartment of Cardiovascular Surgery, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, Guangzhou, 510080, China.
Wei-Zhong ZhuangDepartment of Cardiovascular Surgery, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, Guangzhou, 510080, China.
Jian-Zheng CenDepartment of Cardiovascular Surgery, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, Guangzhou, 510080, China. jamesofsolar@163.com.
Qiang GaoSchool of Medicine, South China University of Technology, Guangzhou, 510006, China. gaoqiang_89@163.com.

Funding

National Key Research and Development Program of China No. 2022YFB4600604National Natural Science Foundation of China No.82300423
6 · The paper itself

Abstract

backgroundThe safety and efficacy of prophylactic corticosteroid administration during the perioperative period of cardiac surgery have undergone extensive and comprehensive examination. In this study, we conducted a bibliometric analysis of publications addressing corticosteroid use in the perioperative period of cardiac surgery, aiming to elucidate the principal research trajectories and emerging trends spanning the past 23 years.

methodsWe performed a search in the Web of Science Core Collection for publications related to the application of corticosteroids during the perioperative period of cardiac surgery, spanning from the year 2000 to October 30, 2023. Bibliometric analysis was conducted employing the biblioshiny package in R, VOSviewer, and CiteSpace.

resultsWe identified 293 eligible publications concerning corticosteroid use during the perioperative period of cardiac surgery. Publication volume increased significantly in 2001 and 2014. Keyword co-occurrence analysis revealed four primary clusters: cardiopulmonary bypass, systemic inflammatory response, methylprednisolone, and dysfunction. Over recent decades, research focus has shifted from examining how prophylactic corticosteroid use attenuates postoperative inflammation to investigating its potential effects on clinical complications following cardiac surgery.

conclusionsConsiderable heterogeneity in inflammatory response phenotypes among individuals may lead to significant differences in the clinical effectiveness of prophylactic corticosteroid interventions. Thus, developing personalized treatment strategies should become a major focus in future research.

Indexed as

Adrenal Cortex HormonesBibliometricsCardiac Surgical ProceduresPostoperative ComplicationsHumansAdrenal Cortex HormonesBibliometricCardiac surgeryCiteSpaceCorticosteroidsVOSviewer

Identifiers

PMID40739233
PMCPMC12312265

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.