Evidence map›Paper›PMID 40739174›Full record

Trial reportBMC anesthesiology2025

Influence of different patient positions on erector spinae plane block spread in modified radical mastectomy: a prospective randomized comparative study.

Adel Ibrahim Hozien, Sahar Ahmed Elkaradawy, Hussein M Agameya, Walid M Ahmed, Ahmed F Elsosy

Abstract readRandomized Controlled TrialComparative Study
In one paragraph

Trial report in BMC anesthesiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Fascial plane blocks in pediatric patients.Journal of anesthesia, analgesia and critical care · 2026
    Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Adel Ibrahim HozienDepartment of Anesthesia and Pain Management, Medical Research Institute, Alexandria University, Alexandria, Egypt. adelhozien@alexu.edu.eg.ORCID http://orcid.org/0000-0001-8715-2549
Sahar Ahmed ElkaradawyDepartment of Anesthesia and Pain Management, Medical Research Institute, Alexandria University, Alexandria, Egypt.ORCID http://orcid.org/0009-0009-2574-2688
Hussein M AgameyaDepartment of Anesthesia and Postoperative Intensive Care, Alexandria Faculty of Medicine, Alexandria University, Alexandria, Egypt.
Walid M AhmedDepartment of Diagnostic Radiology, Medical Research Institute, Alexandria University, Alexandria, Egypt.
Ahmed F ElsosyDepartment of Anesthesia and Pain Management, Medical Research Institute, Alexandria University, Alexandria, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough the analgesic effect of erector spinae plane block (ESPB) has been proven, its efficacy may be influenced by the patient's position during the block.

methodsWe randomly allocated forty patients undergoing unilateral modified radical mastectomy (MRM) with axillary lymph node dissection to receive preoperative ESPB in sitting (Group 1) or lateral position (Group 2), and the patient was kept in position for 15 min, either in the high Fowler's or lateral position. The primary outcome was the dermatomal sensory block and radiocontrast material spread by Computed Tomography (CT) 15 min after the block. Secondary outcomes were the visual analog scale for pain (VAS), opioid consumption, patient satisfaction, and complications.

resultsThere was a significant increase in the dermatomal sensory block in Group 1 compared to Group 2 at midaxillary (confidence interval (C.I) 95% = 0.55, p-value = 0.006) and scapular lines (95% C.I = 0.50, p-value = 0.014); meanwhile, there were insignificant differences at the parasternal and midclavicular lines (p-value = 0.232 and 0.201 respectively). Early CT showed more craniocaudal contrast distribution in a higher percentage of patients in Group 1, with a higher incidence of spread to paravertebral/epidural spaces (though not statistically significant). The VAS, morphine consumption, and patient satisfaction were comparable.

conclusionThe ESPB in the sitting position provided a more significant posterolateral sensory block. The CT evidence of early paravertebral and epidural spread was observed more often in the sitting group, but without statistical significance. ESPB in both patient positions produced comparable postoperative analgesia.

trial registrationPan African Clinical Trials Registry (PACTR) (PACTR202204720116048) on 27/04/2022.

Indexed as

Mastectomy, Modified RadicalNerve BlockPatient PositioningPostoperative PainAdultAnalgesics, OpioidFemaleHumansLymph Node ExcisionMiddle AgedPain MeasurementParaspinal MusclesPatient SatisfactionProspective StudiesAnalgesics, OpioidComputed TomographyErector spinae plane blockOpioid consumptionPatient position and local anesthetic spreadPostoperative analgesiaRegional anesthesia for mastectomy

Identifiers

PMID40739174
PMCPMC12312261

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.