Evidence map›Paper›PMID 40739070›Full record

ArticleEuropean journal of applied physiology2026

Central blood pressure and arterial stiffness among ultramarathon runners across the lifespan.

Joseph D Vondrasek, Soolim Jeong, Omar B El-Kurd, Braxton A Linder, Nina L Stute, Christin Domeier, Thomas G Bissen, James R Bagley, Austin T Robinson, Matthew C Babcock and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European journal of applied physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Joseph D VondrasekCardiovascular and Applied Physiology Laboratory, Department of Health, Nutrition, and Food Sciences, Florida State University, Tallahassee, FL, USA.ORCID http://orcid.org/0009-0006-8573-5955
Soolim JeongNeurovascular Physiology Laboratory, School of Kinesiology, Auburn University, Auburn, AL, USA.ORCID http://orcid.org/0000-0003-1097-9980
Omar B El-KurdMuscle Physiology Laboratory, Department of Kinesiology, San Francisco State University, San Francisco, CA, USA.ORCID http://orcid.org/0000-0003-3413-1773
Braxton A LinderNeurovascular Physiology Laboratory, School of Public Health, Indiana University, Bloomington, IN, USA.ORCID http://orcid.org/0000-0001-6825-5622
Nina L StuteNeurovascular Physiology Laboratory, School of Kinesiology, Auburn University, Auburn, AL, USA.ORCID http://orcid.org/0000-0001-8213-638X
Christin DomeierCardiovascular and Applied Physiology Laboratory, Department of Health, Nutrition, and Food Sciences, Florida State University, Tallahassee, FL, USA.ORCID http://orcid.org/0000-0002-3062-5584
Thomas G BissenCardiovascular and Applied Physiology Laboratory, Department of Health, Nutrition, and Food Sciences, Florida State University, Tallahassee, FL, USA.ORCID http://orcid.org/0009-0003-9660-043X
James R BagleyMuscle Physiology Laboratory, Department of Kinesiology, San Francisco State University, San Francisco, CA, USA.ORCID http://orcid.org/0000-0002-2709-548X
Austin T RobinsonNeurovascular Physiology Laboratory, School of Public Health, Indiana University, Bloomington, IN, USA.ORCID http://orcid.org/0000-0001-8250-3952
Matthew C BabcockDivision of Geriatric Medicine, University of Colorado Denver, Anschutz Medical Campus, Denver, CO, USA.ORCID http://orcid.org/0000-0002-8047-4411
Gregory J GrosickiBiodynamics and Human Performance Center, Department of Health Science and Kinesiology, Georgia Southern University-Armstrong Campus, Savannah, GA, USA.ORCID http://orcid.org/0000-0001-8929-4903
Joseph C WatsoCardiovascular and Applied Physiology Laboratory, Department of Health, Nutrition, and Food Sciences, Florida State University, Tallahassee, FL, USA. jwatso@fsu.edu.ORCID http://orcid.org/0000-0001-7840-0643

Funding

Racial Differences in Serum Sodium and Blood Pressure RegulationK01HL147998 · NHLBI · TRUSTEES OF INDIANA UNIVERSITY · PI ROBINSON, AUSTIN TYLER · 2019 to 2023
$705k
Time-Efficient Inspiratory Muscle Strength Training as a New Approach to Lower Blood Pressure, Improve Respiratory Function, and Reduce Exertional Dyspnea in Adults with ObesityK01HL160772 · NHLBI · FLORIDA STATE UNIVERSITY · PI Joseph Watso · 2022 to 2026
$693k
Neural and Renal Contributions to Hypertension with Androgen Deprivation TherapyK01HL164978 · NHLBI · VIRGINIA COMMONWEALTH UNIVERSITY · PI Matthew C Babcock · 2023 to 2026
$665k
American Heart Association 23CDA1037938NHLBI NIH HHS K01 HL147998NHLBI NIH HHS K01 HL160772NHLBI NIH HHS K01 HL164978NIH HHS K01HL147998NIH HHS K01HL160772NIH HHS K01HL164978
6 · The paper itself

Abstract

aimRegular exercise is beneficial, but more exercise may not always benefit cardiovascular health (extreme exercise hypothesis). This is concerning, because ultramarathon participation is growing, but previous work on cardiovascular health among ultramarathon runners is equivocal. Prior work has not examined this population's age-related differences in prognostic cardiovascular health metrics. PURPOSE: Measure brachial and central BP and arterial stiffness (carotid-to-femoral pulse wave velocity [cfPWV]) among ultramarathon runners.

methodsWe measured supine BP and cfPWV (SphygmoCor-XCEL) among 71 athletes (16 female/55 male; body mass index: 22.6 ± 1.8 kg/m

resultsThere was a significant curvilinear relation between age (46 ± 10; range 26-69 years) and central (116 ± 8 mmHg, R

conclusionsThese are among the first data to characterize central BP and arterial stiffness across a wide age range of ultramarathon runners. Further work is needed to determine the longitudinal changes associated with training for and competing in ultramarathons.

Indexed as

Blood PressureMarathon RunningRunningVascular StiffnessAdultAgedFemaleHumansMaleMiddle AgedPulse Wave AnalysisAgingBlood pressureCentral stiffnessEndurance exerciseUltramarathon

Identifiers

PMID40739070
PMCPMC12356499

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.