Evidence map›Paper›PMID 40738984›Full record

Trial reportTechniques in coloproctology2025

Hemoclip-suture-rubber band traction improves efficiency of colonic ESD: a randomized controlled trial.

X Leng, W Wang, F Wang, H Cang, Y Gao, H Liu, Y Sun

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Techniques in coloproctology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

X LengDepartment of Gastroenterology, Jiangyin Hospital Affiliated to Nantong University, Jiangyin, 214400, Jiangsu, China.
W WangDepartment of Gastroenterology, Jiangyin Hospital Affiliated to Nantong University, Jiangyin, 214400, Jiangsu, China.
F WangDepartment of Gastroenterology, Jiangyin Hospital Affiliated to Nantong University, Jiangyin, 214400, Jiangsu, China. timeswang@163.com.
H CangDepartment of Gastroenterology, Jiangyin Hospital Affiliated to Nantong University, Jiangyin, 214400, Jiangsu, China.
Y GaoDepartment of Gastroenterology, Jiangyin Hospital Affiliated to Nantong University, Jiangyin, 214400, Jiangsu, China.
H LiuDepartment of Gastroenterology, Jiangyin Hospital Affiliated to Nantong University, Jiangyin, 214400, Jiangsu, China.
Y SunDepartment of Pathology, Jiangyin Hospital Affiliated to Nantong University, Jiangyin, 214400, Jiangsu, China.

Funding

The Major Project of the Wuxi Municipal Health Commission Z202410The Science and Technology Development Fund Project of the Affiliated Hospital of Xuzhou Medical University XYFC202402The Science and Technology Plan of the Wuxi Municipal Health Commission T202413
6 · The paper itself

Abstract

objectiveThe objective of this study was to evaluate the efficacy and safety of a novel, simple internal traction method using a hemoclip, suture, and rubber band during endoscopic submucosal dissection (ESD) for colonic lesions.

methodsA total of 96 patients undergoing ESD at Jiangyin Hospital Affiliated with Nantong University between January 2021 and December 2024 were randomized into two groups: Group A (n = 48) underwent conventional ESD, while Group B (n = 48) underwent ESD with hemoclip-suture-rubber band traction. The study included patients with early stage colon cancer, precancerous lesions (e.g., adenomas with high-grade dysplasia), and neuroendocrine tumors. Outcome measures included total procedure time, mucosal dissection time, number of submucosal injections, en bloc resection rate, adverse events, and the size of lesion area.

resultsThe hemoclip-suture-rubber band traction group (Group B) demonstrated significantly shorter total procedure time (72.63 ± 34.14 min versus 85.13 ± 38.18 min, P < 0.05) and mucosal dissection time (53.56 ± 29.03 min versus 71.63 ± 39.18 min, P < 0.001) compared with the conventional ESD group (Group A). Group B also required significantly fewer submucosal injections (1.63 ± 1.23 versus 4.75 ± 1.62, P < 0.001). Lesions in Group B were significantly larger (7.650 [2.857, 10.386] cm

conclusionsThe hemoclip-suture-rubber band traction technique facilitates colonic ESD by reducing procedure time and the need for submucosal injections, especially in larger lesions.While overall safety is comparable to conventional ESD, the potential for muscularis propria injury warrants further study in larger, multicenter trials.This simple and effective method holds promise for improving the efficiency and potentially the safety of colonic ESD.

Indexed as

Colonic NeoplasmsEndoscopic Mucosal ResectionSuture TechniquesTractionAgedColonFemaleHumansMaleMiddle AgedOperative TimeTreatment OutcomeColonic lesionsEndoscopic submucosal dissectionHemoclip–suture–rubber band tractionInternal traction

Identifiers

PMID40738984
PMCPMC12310896

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.